HitPredict

Interactor 1: NFL (P07196)
Neurofilament light polypeptide (NF-L) (68 kDa neurofilament protein) (Neurofilament triplet L protein)
Gene: NEFL

Interactor 2: KIFC3 (Q9BVG8)
Kinesin-like protein KIFC3
Gene: KIFC3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.50	0.559

Property	Details
Experiments	25416956, 26871637
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 543 Hs			1 833
+	Hs
		1031013 K22O_HUMAN (69-414): 6.22e-133: 402: 32.09		KIFC3_HUMAN (1-833): 0: 544: 100.00
+	Hs
		437325 K2C8_HUMAN (69-431): 7.94e-131: 391: 36.44		KIFC3_HUMAN (1-833): 0: 544: 100.00
+	Hs
		474942 VIME_HUMAN (34-402): 6.77e-84: 270: 49.59		KIFC3_HUMAN (1-833): 0: 544: 100.00
+	Hs
		341846 K2C75_HUMAN (2-414): 1.26e-73: 245: 28.20		KIFC3_HUMAN (1-833): 0: 544: 100.00
+	Hs
		570578 GFAP_HUMAN (66-401): 1.36e-70: 234: 48.21		KIFC3_HUMAN (1-833): 0: 544: 100.00
+	Hs
		833354 PERI_HUMAN (9-401): 1.78e-69: 232: 48.12		KIFC3_HUMAN (1-833): 0: 544: 100.00
+	Hs
		1127797 K1H2_HUMAN (8-407): 9.27e-67: 224: 23.69		KIFC3_HUMAN (1-833): 0: 544: 100.00
+	Hs
		1367978 KRT35_HUMAN (2-400): 4.7e-64: 217: 26.68		KIFC3_HUMAN (1-833): 0: 544: 100.00
+	Hs
		566442 K2C5_HUMAN (55-403): 3.07e-59: 208: 31.53		KIFC3_HUMAN (1-833): 0: 544: 100.00
+	Hs
		407335 K2C6B_HUMAN (55-419): 2.72e-59: 207: 30.71		KIFC3_HUMAN (1-833): 0: 544: 100.00
+	Hs
		876497 K2C6C_HUMAN (55-416): 3.1e-59: 207: 30.96		KIFC3_HUMAN (1-833): 0: 544: 100.00
+	Hs
		385319 K2C6A_HUMAN (55-419): 1.39e-57: 203: 30.98		KIFC3_HUMAN (1-833): 0: 544: 100.00
+	Hs
		116877 I6L9F6_HUMAN (219-376): 2.51e-29: 119: 61.01		KIFC3_HUMAN (1-833): 0: 544: 100.00
+	Hs
		245885 PERI_HUMAN (9-401): 1.78e-69: 232: 48.12		KIF1B_HUMAN (452-800): 1.72e-113: 382: 30.35
+	Hs
		116841 I6L9F6_HUMAN (219-376): 2.51e-29: 119: 61.01		KIF1B_HUMAN (452-800): 1.72e-113: 382: 30.35
+	Hs
		104274 K2C6A_HUMAN (55-419): 1.39e-57: 203: 30.98		F5H3M2_HUMAN (44-366): 1.32e-12: 73.6: 12.84