HitPredict

Interactor 1: TJAP1 (Q5JTD0)
Tight junction-associated protein 1 (Protein incorporated later into tight junctions) (Tight junction protein 4)
Gene: TJAP1

Interactor 2: APBA2 (Q99767)
Amyloid-beta A4 precursor protein-binding family A member 2 (Adapter protein X11beta) (Neuron-specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2)
Gene: APBA2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 557 Hs			1 749
+	Hs
		970703 TJAP1_HUMAN (1-557): 0: 780: 100.00		APBA1_HUMAN (57-749): 9.83e-164: 495: 54.09
+	Hs
		331385 TJAP1_HUMAN (1-557): 0: 780: 100.00		APBA3_HUMAN (263-749): 3.09e-107: 340: 50.61
+	Hs
		942356 TJAP1_HUMAN (1-557): 0: 780: 100.00		DLG4_HUMAN (559-730): 2.89e-34: 142: 17.50
+	Hs
		1021510 TJAP1_HUMAN (1-557): 0: 780: 100.00		DLG1_HUMAN (442-730): 2.01e-28: 124: 16.24
+	Mm
		1143514 TJAP1_MOUSE (1-557): 0: 710: 83.84		DLG4_MOUSE (559-730): 2.81e-34: 142: 17.50
+	Mm
		936190 TJAP1_MOUSE (1-557): 0: 710: 83.84		DLG3_MOUSE (653-746): 1.38e-09: 63.5: 21.50
+	Hs
		942376 BEGIN_HUMAN (39-303): 2.73e-100: 317: 38.87		DLG4_HUMAN (559-730): 2.89e-34: 142: 17.50
+	Mm
		1143333 BEGIN_MOUSE (39-303): 1.11e-95: 305: 37.36		DLG4_MOUSE (559-730): 2.81e-34: 142: 17.50