HitPredict

Interactor 1: SYN1 (P09951)
Synapsin-1 (Synapsin I)
Gene: SYN1

Interactor 2: TAU (P19332)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: Mapt

Species: Rattus norvegicus

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	32357304
Identification Methods	cross-linking study
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0014069 - postsynaptic density GO:0019901 - protein kinase binding GO:0030424 - axon GO:0030425 - dendrite GO:0044297 - cell body and 1 others more... GO:0050808 - synapse organization
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 704 Rn			1 752
+	Rn
		582009 SYN2_RAT (1-454): 0: 580: 65.51		TAU_RAT (1-752): 2.4e-95: 314: 100.00
+	Rn
		94234 SYN2_RAT (1-454): 0: 580: 65.51		F1LST4_RAT (1-751): 5.68e-95: 314: 99.87
+	Hs
		497380 SYN2_HUMAN (1-443): 0: 607: 66.15		TAU_HUMAN (1-752): 2.05e-72: 253: 71.86
+	Rn
		94125 SYN1_RAT (1-704): 1.38e-177: 525: 100.00		F1LST4_RAT (1-751): 5.68e-95: 314: 99.87
+	Hs
		496247 SYN1_HUMAN (1-704): 4.05e-168: 500: 95.75		TAU_HUMAN (1-752): 2.05e-72: 253: 71.86
+	Mm
		292463 SYN1_MOUSE (1-704): 5.81e-179: 528: 97.73		MTAP2_MOUSE (49-752): 4.26e-36: 149: 25.07
+	Rn
		582007 SYNJ1_RAT (396-704): 2.11e-12: 73: 14.29		TAU_RAT (1-752): 2.4e-95: 314: 100.00
+	Rn
		94231 SYNJ1_RAT (396-704): 2.11e-12: 73: 14.29		F1LST4_RAT (1-751): 5.68e-95: 314: 99.87
+	Hs
		497383 CBP_HUMAN (376-687): 4.03e-26: 117: 14.60		TAU_HUMAN (1-752): 2.05e-72: 253: 71.86
+	Mm
		88453 D3Z656_MOUSE (341-700): 8.45e-17: 87.3: 14.52		TAU_MOUSE (1-752): 1.92e-82: 279: 89.52
+	Hs
		203203 SYNJ1_HUMAN (396-685): 4.37e-11: 68.8: 11.51		TAU_HUMAN (1-752): 2.05e-72: 253: 71.86
+	Hs
		496630 SC24C_HUMAN (503-703): 1.69e-09: 63.4: 15.09		TAU_HUMAN (1-752): 2.05e-72: 253: 71.86
+	Hs
		302246 SC31A_HUMAN (345-636): 8.88e-09: 61.1: 12.83		TAU_HUMAN (1-752): 2.05e-72: 253: 71.86
+	Hs
		1056910 CBP_HUMAN (376-687): 4.03e-26: 117: 14.60		MDC1_HUMAN (4-740): 1.03e-26: 119: 9.08
+	Hs
		1170076 CBP_HUMAN (376-687): 4.03e-26: 117: 14.60		SRCAP_HUMAN (179-745): 4.41e-11: 68.9: 10.92
+	Mm
		1351630 PCLO_MOUSE (417-699): 1.84e-25: 115: 15.04		PCLO_MOUSE (1-751): 6.24e-11: 68.5: 10.66
+	Dm
		113976 M9PB30_DROME (521-700): 9.71e-09: 61.1: 15.59		M9PB30_DROME (164-747): 7.63e-20: 97.8: 9.45