HitPredict

Interactor 1: IGF1R (P08069)
Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain]
Gene: IGF1R

Interactor 2: HS90B (P08238)
Heat shock protein HSP 90-beta (HSP 90) (Heat shock 84 kDa) (HSP 84) (HSP84) (Heat shock protein family C member 3)
Gene: HSP90AB1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 27684187, 22939624
Identification Methods affinity chromatography technology, luminescence based mammalian interactome mapping
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains HSP90~PK_Tyr_Ser-Thr
Common GO terms GO:0005524 - ATP binding
GO:0005886 - plasma membrane
GO:0016020 - membrane
GO:0043066 - negative regulation of apoptotic process
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1367
Hs

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Service provided by Combinatics, Japan

Last updated: 11Aug2025