HitPredict

Interactor 1: RHOC (P08134)
Rho-related GTP-binding protein RhoC (Rho cDNA clone 9) (h9)
Gene: RHOC

Interactor 2: PTN12 (Q05209)
Tyrosine-protein phosphatase non-receptor type 12 (EC 3.1.3.48) (PTP-PEST) (Protein-tyrosine phosphatase G1) (PTPG1)
Gene: PTPN12

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	31980649, unassigned2173
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 193 Hs			1 780
+	Hs
		961979 RHOA_HUMAN (1-193): 4.28e-81: 240: 91.71		PTN12_HUMAN (1-780): 0: 573: 100.00
+	Hs
		611069 RHOA_HUMAN (1-193): 4.28e-81: 240: 91.71		PTN1_HUMAN (27-414): 3.72e-126: 385: 25.30
+	Hs
		611077 RAC1_HUMAN (1-193): 6.84e-81: 240: 57.22		PTN1_HUMAN (27-414): 3.72e-126: 385: 25.30
+	Hs
		961982 RHOA_HUMAN (1-193): 4.28e-81: 240: 91.71		PTN11_HUMAN (7-359): 5.77e-124: 385: 29.65
+	Hs
		466100 RHOC_HUMAN (1-193): 7.6e-80: 237: 100.00		PTN1_HUMAN (27-414): 3.72e-126: 385: 25.30
+	Hs
		607565 RHOA_HUMAN (1-193): 4.28e-81: 240: 91.71		PTN2_HUMAN (24-397): 1.32e-121: 373: 24.09
+	Hs
		466099 RHOC_HUMAN (1-193): 7.6e-80: 237: 100.00		PTN2_HUMAN (24-397): 1.32e-121: 373: 24.09
+	Hs
		962011 RHOA_HUMAN (1-193): 4.28e-81: 240: 91.71		PTPRS_HUMAN (8-299): 3.53e-97: 333: 31.65
+	Hs
		988333 RAC1_HUMAN (1-193): 6.84e-81: 240: 57.22		PTPRS_HUMAN (8-299): 3.53e-97: 333: 31.65
+	Hs
		466235 RHOC_HUMAN (1-193): 7.6e-80: 237: 100.00		PTPRS_HUMAN (8-299): 3.53e-97: 333: 31.65
+	Hs
		522635 RHOA_HUMAN (1-193): 4.28e-81: 240: 91.71		PTPRF_HUMAN (8-293): 3.84e-90: 313: 32.65
+	Hs
		522641 RAC1_HUMAN (1-193): 6.84e-81: 240: 57.22		PTPRF_HUMAN (8-293): 3.84e-90: 313: 32.65
+	Hs
		466080 RHOC_HUMAN (1-193): 7.6e-80: 237: 100.00		PTPRF_HUMAN (8-293): 3.84e-90: 313: 32.65
+	Hs
		705696 RAC1_HUMAN (1-193): 6.84e-81: 240: 57.22		PTPRM_HUMAN (7-293): 5.62e-62: 229: 24.75
+	Hs
		962070 RHOA_HUMAN (1-193): 4.28e-81: 240: 91.71		PTPRK_HUMAN (17-293): 1.38e-59: 221: 26.67
+	Hs
		659007 RHOA_HUMAN (1-193): 4.28e-81: 240: 91.71		PTPRG_HUMAN (8-325): 3.58e-53: 202: 23.33
+	Hs
		659013 RAC1_HUMAN (1-193): 6.84e-81: 240: 57.22		PTPRG_HUMAN (8-325): 3.58e-53: 202: 23.33
+	Hs
		961995 RHOA_HUMAN (1-193): 4.28e-81: 240: 91.71		PTPRJ_HUMAN (49-297): 6.26e-46: 179: 39.13
+	Hs
		988321 RAC1_HUMAN (1-193): 6.84e-81: 240: 57.22		PTPRJ_HUMAN (49-297): 6.26e-46: 179: 39.13
+	Hs
		466226 RHOC_HUMAN (1-193): 7.6e-80: 237: 100.00		PTPRJ_HUMAN (49-297): 6.26e-46: 179: 39.13