HitPredict

Interactor 1: RHOC (P08134)
Rho-related GTP-binding protein RhoC (Rho cDNA clone 9) (h9)
Gene: RHOC

Interactor 2: IL1AP (Q9NPH3)
Interleukin-1 receptor accessory protein (IL-1 receptor accessory protein) (IL-1RAcP) (EC 3.2.2.6) (Interleukin-1 receptor 3) (IL-1R-3) (IL-1R3)
Gene: IL1RAP

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 193 Hs			1 570
+	Hs
		988736 RAC1_HUMAN (1-193): 6.84e-81: 240: 57.22		IL1AP_HUMAN (1-570): 1.38e-117: 361: 100.00
+	Hs
		978326 RHOB_HUMAN (1-191): 6.1e-74: 222: 84.82		IL1AP_HUMAN (1-570): 1.38e-117: 361: 100.00
+	Hs
		575751 RAC1_HUMAN (1-193): 6.84e-81: 240: 57.22		IL1R1_HUMAN (67-566): 2.42e-79: 262: 22.59
+	Hs
		332121 RAC1_HUMAN (1-193): 6.84e-81: 240: 57.22		I18RA_HUMAN (62-568): 4.44e-64: 222: 23.56
+	Hs
		962694 RHOA_HUMAN (1-193): 4.28e-81: 240: 91.71		ROBO1_HUMAN (1-281): 5.23e-39: 155: 14.53
+	Hs
		988870 RAC1_HUMAN (1-193): 6.84e-81: 240: 57.22		ROBO1_HUMAN (1-281): 5.23e-39: 155: 14.53
+	Hs
		466555 RHOC_HUMAN (1-193): 7.6e-80: 237: 100.00		ROBO1_HUMAN (1-281): 5.23e-39: 155: 14.53
+	Hs
		955810 CDC42_HUMAN (1-193): 8.86e-78: 232: 51.30		ROBO1_HUMAN (1-281): 5.23e-39: 155: 14.53
+	Hs
		978442 RHOB_HUMAN (1-191): 6.1e-74: 222: 84.82		ROBO1_HUMAN (1-281): 5.23e-39: 155: 14.53
+	Hs
		955439 CDC42_HUMAN (1-193): 8.86e-78: 232: 51.30		PXDN_HUMAN (137-481): 2.19e-34: 141: 10.80
+	Hs
		978319 RHOB_HUMAN (1-191): 6.1e-74: 222: 84.82		ROBO2_HUMAN (2-473): 2.64e-35: 144: 11.27
+	Ce
		145082 RAC1_CAEEL (1-193): 3.47e-81: 240: 53.89		UNC89_CAEEL (1-131): 9.63e-13: 73.6: 9.85
+	Ce
		110130 G5EBV3_CAEEL (2-193): 4.53e-79: 235: 50.52		UNC89_CAEEL (1-131): 9.63e-13: 73.6: 9.85
+	Ce
		145083 CDC42_CAEEL (1-193): 2.08e-75: 226: 49.74		UNC89_CAEEL (1-131): 9.63e-13: 73.6: 9.85
+	Ce
		145089 RHO1_CAEEL (1-192): 1.45e-75: 226: 83.33		UNC89_CAEEL (1-131): 9.63e-13: 73.6: 9.85
+	Hs
		955204 CDC42_HUMAN (1-193): 8.86e-78: 232: 51.30		MYLK_HUMAN (8-257): 3.62e-10: 65.1: 11.37