Interactor 1: ACM4 (P08173)
Muscarinic acetylcholine receptor M4
Gene: CHRM4
Interactor 2: 5HT2C (P28335)
5-hydroxytryptamine receptor 2C (5-HT-2C) (5-HT2C) (5-HTR2C) (5-hydroxytryptamine receptor 1C) (5-HT-1C) (5-HT1C) (Serotonin receptor 2C)
Gene: HTR2C
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 15518545 |
| Identification Methods | cross-linking study |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | 7tm_1~7tm_1 |
| Common GO terms | GO:0005886 - plasma membrane GO:0007187 - G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger GO:0007268 - chemical synaptic transmission GO:0030425 - dendrite GO:0045202 - synapse |
| Homologous interactions | 19 |
Homologous interactions
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025