HitPredict

Interactor 1: HS90B (P08238)
Heat shock protein HSP 90-beta (HSP 90) (Heat shock 84 kDa) (HSP 84) (HSP84) (Heat shock protein family C member 3)
Gene: HSP90AB1

Interactor 2: F10A1 (P50502)
Hsc70-interacting protein (Hip) (Aging-associated protein 2) (Progesterone receptor-associated p48 protein) (Protein FAM10A1) (Putative tumor suppressor ST13) (Renal carcinoma antigen NY-REN-33) (Suppression of tumorigenicity 13 protein)
Gene: ST13

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34349018
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	HSP90~STI1-HOP_DP, HSP90~TPR_8
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0006457 - protein folding GO:0046983 - protein dimerization activity GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 724 Hs			1 369
+	Hs
		461279 HS90A_HUMAN (1-724): 0: 1069: 85.25		F10A1_HUMAN (1-369): 2.03e-65: 213: 100.00
+	Mm
		547287 HS90B_MOUSE (1-724): 0: 1086: 99.59		CHIP_MOUSE (91-356): 3.88e-43: 153: 14.29
+	Hs
		468915 HS90B_HUMAN (1-724): 0: 1083: 100.00		CHIP_HUMAN (89-356): 1.1e-43: 155: 14.19
+	Hs
		468336 HS90B_HUMAN (1-724): 0: 1083: 100.00		FKBP5_HUMAN (17-285): 1.14e-40: 150: 14.34
+	Mm
		547256 HS90B_MOUSE (1-724): 0: 1086: 99.59		PPP5_MOUSE (91-270): 1.91e-38: 145: 20.44
+	Hs
		226675 HS90B_HUMAN (1-724): 0: 1083: 100.00		SGTA_HUMAN (35-337): 1.72e-40: 147: 16.12
+	Hs
		468282 HS90B_HUMAN (1-724): 0: 1083: 100.00		FKBP4_HUMAN (18-276): 1.83e-39: 147: 16.67
+	Hs
		468210 HS90B_HUMAN (1-724): 0: 1083: 100.00		PPP5_HUMAN (91-270): 1.44e-38: 145: 21.55
+	Hs
		117620 K9JA46_HUMAN (1-724): 0: 1069: 85.25		FKBP5_HUMAN (17-285): 1.14e-40: 150: 14.34
+	Hs
		461443 HS90A_HUMAN (1-724): 0: 1069: 85.25		FKBP5_HUMAN (17-285): 1.14e-40: 150: 14.34
+	Hs
		117619 K9JA46_HUMAN (1-724): 0: 1069: 85.25		FKBP4_HUMAN (18-276): 1.83e-39: 147: 16.67
+	Hs
		226672 HS90A_HUMAN (1-724): 0: 1069: 85.25		SGTA_HUMAN (35-337): 1.72e-40: 147: 16.12
+	Hs
		461376 HS90A_HUMAN (1-724): 0: 1069: 85.25		FKBP4_HUMAN (18-276): 1.83e-39: 147: 16.67
+	Hs
		117618 K9JA46_HUMAN (1-724): 0: 1069: 85.25		PPP5_HUMAN (91-270): 1.44e-38: 145: 21.55
+	Hs
		461300 HS90A_HUMAN (1-724): 0: 1069: 85.25		PPP5_HUMAN (91-270): 1.44e-38: 145: 21.55
+	Hs
		317976 HS90B_HUMAN (1-724): 0: 1083: 100.00		TOM70_HUMAN (86-244): 3.57e-23: 103: 26.83
+	Hs
		185366 HS90B_HUMAN (1-724): 0: 1083: 100.00		OGT1_HUMAN (103-355): 6.94e-19: 90.4: 12.45
+	Hs
		317975 HS90A_HUMAN (1-724): 0: 1069: 85.25		TOM70_HUMAN (86-244): 3.57e-23: 103: 26.83
+	Hs
		185361 HS90A_HUMAN (1-724): 0: 1069: 85.25		OGT1_HUMAN (103-355): 6.94e-19: 90.4: 12.45
+	Hs
		468809 HS90B_HUMAN (1-724): 0: 1083: 100.00		RPAP3_HUMAN (3-358): 8.91e-09: 59.2: 10.55