HitPredict

Interactor 1: RU2B (P08579)
U2 small nuclear ribonucleoprotein B'' (U2 snRNP B'')
Gene: SNRPB2

Interactor 2: RNPS1 (Q15287)
RNA-binding protein with serine-rich domain 1 (SR-related protein LDC2)
Gene: RNPS1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	17353931
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016607 - nuclear speck
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 225 Hs			1 305
+	Hs
		471837 RU2B_HUMAN (1-225): 7.23e-51: 166: 100.00		SART3_HUMAN (2-302): 1.68e-38: 146: 16.32
+	Hs
		471948 RU2B_HUMAN (1-225): 7.23e-51: 166: 100.00		PPIE_HUMAN (159-297): 4.43e-33: 125: 17.73
+	Hs
		478048 SNRPA_HUMAN (2-225): 4.07e-42: 145: 48.56		SART3_HUMAN (2-302): 1.68e-38: 146: 16.32
+	Hs
		471956 RU2B_HUMAN (1-225): 7.23e-51: 166: 100.00		RBM8A_HUMAN (95-239): 7.05e-31: 115: 21.38
+	Sc
		1025660 NAM8_YEAST (1-224): 6.19e-42: 150: 16.09		NCBP2_YEAST (127-236): 1.25e-33: 124: 25.46
+	Hs
		478053 SNRPA_HUMAN (2-225): 4.07e-42: 145: 48.56		RNPS1_HUMAN (1-234): 1.24e-34: 129: 100.00
+	Hs
		478258 SNRPA_HUMAN (2-225): 4.07e-42: 145: 48.56		PPIE_HUMAN (159-297): 4.43e-33: 125: 17.73
+	Hs
		211259 SNRPA_HUMAN (2-225): 4.07e-42: 145: 48.56		RFOX2_HUMAN (44-274): 2.33e-31: 122: 13.25
+	Dm
		847883 SNRPA_DROME (1-225): 1.52e-43: 147: 64.44		PPIE_DROME (157-291): 2.08e-31: 120: 18.52
+	Hs
		478278 SNRPA_HUMAN (2-225): 4.07e-42: 145: 48.56		RBM8A_HUMAN (95-239): 7.05e-31: 115: 21.38
+	Hs
		477958 SNRPA_HUMAN (2-225): 4.07e-42: 145: 48.56		NCBP2_HUMAN (128-271): 1.09e-30: 114: 18.06
+	Hs
		478003 SNRPA_HUMAN (2-225): 4.07e-42: 145: 48.56		TIAR_HUMAN (155-250): 1.51e-18: 86.9: 27.08
+	Hs
		477926 SNRPA_HUMAN (2-225): 4.07e-42: 145: 48.56		TIA1_HUMAN (156-251): 2.6e-18: 86.1: 27.08
+	Sc
		826553 MSL1_YEAST (7-91): 8.07e-27: 100: 30.59		NCBP2_YEAST (127-236): 1.25e-33: 124: 25.46
+	Hs
		211272 PTBP1_HUMAN (5-224): 4.2e-17: 81.2: 16.07		RFOX2_HUMAN (44-274): 2.33e-31: 122: 13.25
+	Hs
		687361 PTBP1_HUMAN (5-224): 4.2e-17: 81.2: 16.07		NCBP2_HUMAN (128-271): 1.09e-30: 114: 18.06
+	Hs
		550311 PAP1L_HUMAN (8-151): 1.01e-18: 85.9: 13.79		PABP1_HUMAN (65-252): 1.03e-21: 97.3: 16.32
+	Mm
		710979 TIA1_MOUSE (2-160): 4.61e-17: 80.5: 14.29		PABP1_MOUSE (65-252): 1.28e-21: 96.9: 16.32
+	Hs
		550137 TIA1_HUMAN (2-160): 1.26e-16: 79.4: 13.04		PABP1_HUMAN (65-252): 1.03e-21: 97.3: 16.32
+	Hs
		1197178 PAP1L_HUMAN (8-151): 1.01e-18: 85.9: 13.79		PABP3_HUMAN (153-248): 3.53e-17: 83.8: 26.04