HitPredict

Interactor 1: SNRPA (P09012)
U1 small nuclear ribonucleoprotein A (U1 snRNP A) (U1-A) (U1A)
Gene: SNRPA

Interactor 2: RNPS1 (Q15287)
RNA-binding protein with serine-rich domain 1 (SR-related protein LDC2)
Gene: RNPS1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	1.00	0.896

Property	Details
Experiments	26496610, 17353931, 35271311, 39522233
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 282 Hs			1 305
+	Hs
		478048 SNRPA_HUMAN (1-282): 1.06e-59: 193: 100.00		SART3_HUMAN (2-302): 1.68e-38: 146: 16.32
+	Hs
		471837 RU2B_HUMAN (5-282): 1.38e-59: 190: 46.40		SART3_HUMAN (2-302): 1.68e-38: 146: 16.32
+	Hs
		471841 RU2B_HUMAN (5-282): 1.38e-59: 190: 46.40		RNPS1_HUMAN (1-234): 1.24e-34: 129: 100.00
+	Hs
		478258 SNRPA_HUMAN (1-282): 1.06e-59: 193: 100.00		PPIE_HUMAN (159-297): 4.43e-33: 125: 17.73
+	Hs
		211259 SNRPA_HUMAN (1-282): 1.06e-59: 193: 100.00		RFOX2_HUMAN (44-274): 2.33e-31: 122: 13.25
+	Hs
		471948 RU2B_HUMAN (5-282): 1.38e-59: 190: 46.40		PPIE_HUMAN (159-297): 4.43e-33: 125: 17.73
+	Hs
		211272 PTBP1_HUMAN (1-281): 2.59e-55: 189: 20.42		RFOX2_HUMAN (44-274): 2.33e-31: 122: 13.25
+	Hs
		478278 SNRPA_HUMAN (1-282): 1.06e-59: 193: 100.00		RBM8A_HUMAN (95-239): 7.05e-31: 115: 21.38
+	Hs
		477958 SNRPA_HUMAN (1-282): 1.06e-59: 193: 100.00		NCBP2_HUMAN (128-271): 1.09e-30: 114: 18.06
+	Hs
		471956 RU2B_HUMAN (5-282): 1.38e-59: 190: 46.40		RBM8A_HUMAN (95-239): 7.05e-31: 115: 21.38
+	Hs
		687361 PTBP1_HUMAN (1-281): 2.59e-55: 189: 20.42		NCBP2_HUMAN (128-271): 1.09e-30: 114: 18.06
+	Hs
		344371 PTBP3_HUMAN (2-281): 3.3e-49: 172: 19.44		PPIE_HUMAN (159-297): 4.43e-33: 125: 17.73
+	Hs
		211248 PTBP3_HUMAN (2-281): 3.3e-49: 172: 19.44		RFOX2_HUMAN (44-274): 2.33e-31: 122: 13.25
+	Hs
		1145213 RBY1F_HUMAN (1-280): 7.91e-46: 162: 17.48		RNPS1_HUMAN (1-234): 1.24e-34: 129: 100.00
+	Sc
		743561 RU1A_YEAST (1-281): 3.83e-48: 163: 20.42		NCBP2_YEAST (127-236): 1.25e-33: 124: 25.46
+	Hs
		344138 PTBP3_HUMAN (2-281): 3.3e-49: 172: 19.44		NCBP2_HUMAN (128-271): 1.09e-30: 114: 18.06
+	Hs
		478003 SNRPA_HUMAN (1-282): 1.06e-59: 193: 100.00		TIAR_HUMAN (155-250): 1.51e-18: 86.9: 27.08
+	Hs
		477926 SNRPA_HUMAN (1-282): 1.06e-59: 193: 100.00		TIA1_HUMAN (156-251): 2.6e-18: 86.1: 27.08
+	Hs
		344105 PTBP3_HUMAN (2-281): 3.3e-49: 172: 19.44		TIA1_HUMAN (156-251): 2.6e-18: 86.1: 27.08
+	At
		1192847 Q9ASW4_ARATH (11-281): 7.75e-45: 156: 22.91		CP29A_ARATH (108-252): 8.52e-20: 90: 20.00