HitPredict

Interactor 1: ITA5 (P08648)
Integrin alpha-5 (CD49 antigen-like family member E) (Fibronectin receptor subunit alpha) (Integrin alpha-F) (VLA-5) (CD antigen CD49e) [Cleaved into: Integrin alpha-5 heavy chain; Integrin alpha-5 light chain]
Gene: ITGA5

Interactor 2: LEG12 (Q96DT0)
Galectin-12 (Gal-12) (Galectin-related inhibitor of proliferation)
Gene: LGALS12

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1049 Hs			1 336
+	Hs
		473654 ITA5_HUMAN (1-1049): 0: 1230: 100.00		LEG3_HUMAN (188-333): 1.02e-46: 160: 22.37
+	Hs
		125162 ITA5_HUMAN (1-1049): 0: 1230: 100.00		LEG9_HUMAN (6-181): 1.35e-42: 152: 29.61
+	Hs
		127253 ITA5_HUMAN (1-1049): 0: 1230: 100.00		LEG8_HUMAN (13-180): 1.91e-37: 137: 27.06
+	Hs
		473644 ITA5_HUMAN (1-1049): 0: 1230: 100.00		LEG1_HUMAN (219-334): 8.04e-35: 125: 23.39
+	Hs
		480748 ITA8_HUMAN (18-1049): 0: 1121: 45.01		LEG1_HUMAN (219-334): 8.04e-35: 125: 23.39
+	Hs
		127247 ITAV_HUMAN (39-1028): 0: 1084: 45.89		LEG8_HUMAN (13-180): 1.91e-37: 137: 27.06
+	Hs
		447961 ITAV_HUMAN (39-1028): 0: 1084: 45.89		LEG1_HUMAN (219-334): 8.04e-35: 125: 23.39
+	Mm
		147612 ITA2B_MOUSE (14-1032): 0: 946: 37.03		LEG9_MOUSE (6-181): 2.52e-45: 159: 30.17
+	Hs
		125195 ITA4_HUMAN (18-1039): 0: 917: 24.62		LEG9_HUMAN (6-181): 1.35e-42: 152: 29.61
+	Hs
		609576 ITA6_HUMAN (28-1045): 0: 904: 24.71		LEG3_HUMAN (188-333): 1.02e-46: 160: 22.37
+	Hs
		127265 ITA4_HUMAN (18-1039): 0: 917: 24.62		LEG8_HUMAN (13-180): 1.91e-37: 137: 27.06
+	Hs
		480676 ITA4_HUMAN (18-1039): 0: 917: 24.62		LEG1_HUMAN (219-334): 8.04e-35: 125: 23.39
+	Hs
		127278 ITA6_HUMAN (28-1045): 0: 904: 24.71		LEG8_HUMAN (13-180): 1.91e-37: 137: 27.06
+	Hs
		127326 ITA7_HUMAN (17-1045): 0: 894: 26.21		LEG8_HUMAN (13-180): 1.91e-37: 137: 27.06
+	Hs
		480703 ITA6_HUMAN (28-1045): 0: 904: 24.71		LEG1_HUMAN (219-334): 8.04e-35: 125: 23.39
+	Hs
		480788 ITA9_HUMAN (38-1042): 0: 899: 26.33		LEG1_HUMAN (219-334): 8.04e-35: 125: 23.39
+	Hs
		480786 ITA7_HUMAN (17-1045): 0: 894: 26.21		LEG1_HUMAN (219-334): 8.04e-35: 125: 23.39
+	Hs
		127281 ITA3_HUMAN (18-1042): 0: 804: 25.41		LEG8_HUMAN (13-180): 1.91e-37: 137: 27.06
+	Hs
		480711 ITA3_HUMAN (18-1042): 0: 804: 25.41		LEG1_HUMAN (219-334): 8.04e-35: 125: 23.39
+	Hs
		127308 ITA1_HUMAN (19-194): 1.48e-36: 152: 27.37		LEG8_HUMAN (13-180): 1.91e-37: 137: 27.06