HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: M3K1 (Q13233)
Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1) (EC 2.3.2.27)
Gene: MAP3K1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	16845370
Identification Methods	pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~ubiquitin
Common GO terms	GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 685 Hs			1 1512
+	Hs
		475017 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		M3K1_HUMAN (1-1512): 0: 1994: 100.00
+	Hs
		475314 UBC_HUMAN (1-685): 0: 846: 100.00		KPCA_HUMAN (963-1509): 9.28e-133: 428: 18.93
+	Hs
		408535 UBC_HUMAN (1-685): 0: 846: 100.00		KPCB_HUMAN (899-1509): 2.67e-127: 413: 15.40
+	Hs
		476266 UBC_HUMAN (1-685): 0: 846: 100.00		M3K3_HUMAN (1243-1505): 1.2e-51: 195: 44.03
+	Hs
		476603 UBC_HUMAN (1-685): 0: 846: 100.00		M3K2_HUMAN (1238-1505): 3.52e-50: 191: 42.13
+	Hs
		476663 UBC_HUMAN (1-685): 0: 846: 100.00		M3K4_HUMAN (1242-1505): 6.41e-38: 158: 33.21
+	At
		1091641 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		KIN10_ARATH (1228-1509): 1.62e-124: 400: 29.33
+	At
		955189 UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63		KIN11_ARATH (1227-1510): 7.29e-122: 393: 28.42
+	Rn
		934619 UBC_RAT (1-108): 1.27e-29: 127: 90.74		KPCB_RAT (899-1509): 8.16e-127: 412: 15.40
+	Rn
		930581 UBC_RAT (1-108): 1.27e-29: 127: 90.74		KPCG_RAT (909-1509): 1.44e-124: 407: 16.30
+	Hs
		408534 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		KPCB_HUMAN (899-1509): 2.67e-127: 413: 15.40
+	Hs
		625332 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		CDK2_HUMAN (1243-1509): 1.1e-104: 337: 25.85
+	Hs
		1306392 Q9UFQ0_HUMAN (295-533): 4.21e-87: 274: 99.58		M3K3_HUMAN (1243-1505): 1.2e-51: 195: 44.03
+	Hs
		397911 ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69		CDK3_HUMAN (1243-1510): 4.87e-105: 338: 27.21
+	Hs
		924126 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		M3K3_HUMAN (1243-1505): 1.2e-51: 195: 44.03
+	Hs
		924221 RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00		M3K2_HUMAN (1238-1505): 3.52e-50: 191: 42.13
+	Hs
		475158 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		M3K3_HUMAN (1243-1505): 1.2e-51: 195: 44.03
+	Hs
		475248 UBB_HUMAN (1-77): 7.83e-26: 108: 98.70		M3K2_HUMAN (1238-1505): 3.52e-50: 191: 42.13