HitPredict

Interactor 1: K1H1 (Q15323)
Keratin, type I cuticular Ha1 (Hair keratin, type I Ha1) (Keratin-31) (K31)
Gene: KRT31

Interactor 2: KLC4 (Q9NSK0)
Kinesin light chain 4 (KLC 4) (Kinesin-like protein 8)
Gene: KLC4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.82	0.50	0.643

Property	Details
Experiments	25416956, 32296183, 33961781, unassigned1304
Identification Methods	two hybrid, affinity chromatography technology, two hybrid prey pooling approach, two hybrid array, validated two hybrid, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 416 Hs			1 619
+	Hs
		475703 K1C19_HUMAN (48-366): 8.95e-141: 409: 56.11		KLC4_HUMAN (1-619): 5.86e-129: 394: 100.00
+	Hs
		1230349 K1C39_HUMAN (36-416): 1.52e-133: 394: 62.30		KLC4_HUMAN (1-619): 5.86e-129: 394: 100.00
+	Hs
		476403 K1C16_HUMAN (54-382): 2.64e-115: 347: 58.36		KLC4_HUMAN (1-619): 5.86e-129: 394: 100.00
+	Hs
		618119 K1C15_HUMAN (55-367): 1.79e-111: 336: 57.96		KLC4_HUMAN (1-619): 5.86e-129: 394: 100.00
+	Hs
		566315 K1C13_HUMAN (50-373): 2.1e-108: 328: 56.00		KLC4_HUMAN (1-619): 5.86e-129: 394: 100.00
+	Hs
		49910 A1A4E9_HUMAN (50-373): 1.98e-107: 326: 55.39		KLC4_HUMAN (1-619): 5.86e-129: 394: 100.00
+	Hs
		300509 KRT34_HUMAN (1-391): 2.98e-95: 292: 89.00		KLC4_HUMAN (1-619): 5.86e-129: 394: 100.00
+	Hs
		1127686 KT33B_HUMAN (1-414): 1.1e-82: 260: 91.55		KLC4_HUMAN (1-619): 5.86e-129: 394: 100.00
+	Hs
		1060519 K1H1_HUMAN (1-416): 2.67e-90: 280: 100.00		KLC1_HUMAN (1-544): 8.98e-98: 311: 68.99
+	Hs
		185395 K1C10_HUMAN (52-361): 3.2e-95: 298: 56.01		OGT1_HUMAN (71-587): 4.97e-49: 186: 15.47
+	Hs
		618051 K1C15_HUMAN (55-367): 1.79e-111: 336: 57.96		KLC3_HUMAN (290-617): 7.47e-28: 119: 32.74
+	Hs
		566278 K1C13_HUMAN (50-373): 2.1e-108: 328: 56.00		KLC3_HUMAN (290-617): 7.47e-28: 119: 32.74
+	Hs
		49898 A1A4E9_HUMAN (50-373): 1.98e-107: 326: 55.39		KLC3_HUMAN (290-617): 7.47e-28: 119: 32.74
+	Mm
		1239390 K2C73_MOUSE (9-412): 7.81e-96: 298: 22.41		NPHP3_MOUSE (314-617): 4.22e-20: 97.4: 16.86
+	Mm
		385202 K1C10_MOUSE (59-363): 6.62e-94: 295: 56.27		NPHP3_MOUSE (314-617): 4.22e-20: 97.4: 16.86
+	Mm
		1274370 K2C79_MOUSE (9-393): 7.17e-87: 275: 25.00		NPHP3_MOUSE (314-617): 4.22e-20: 97.4: 16.86
+	Mm
		1274371 K2C5_MOUSE (19-381): 1.31e-81: 263: 25.48		NPHP3_MOUSE (314-617): 4.22e-20: 97.4: 16.86