HitPredict

Interactor 1: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Interactor 2: PLEC (Q15149)
Plectin (PCN) (PLTN) (Hemidesmosomal protein 1) (HD1) (Plectin-1)
Gene: PLEC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	28190767
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005741 - mitochondrial outer membrane GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 685 Hs			1 4684
+	Hs
		397977 ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69		PLEC_HUMAN (1-4684): 0: 1783: 100.00
+	Mm
		477041 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		PLEC_MOUSE (1-4684): 0: 1747: 93.29
+	Hs
		475541 UBC_HUMAN (1-685): 0: 846: 100.00		EPIPL_HUMAN (3039-3941): 6.03e-42: 174: 27.75
+	Hs
		476576 UBC_HUMAN (1-685): 0: 846: 100.00		MACF1_HUMAN (3704-4616): 3.72e-10: 69.3: 14.92
+	Rn
		1144315 UBC_RAT (1-108): 1.27e-29: 127: 90.74		ACTN1_RAT (153-876): 3.38e-112: 383: 24.07
+	Mm
		476860 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		ACTN1_MOUSE (153-876): 2.62e-111: 381: 24.20
+	Hs
		397748 ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69		ACTN1_HUMAN (153-876): 1.96e-112: 384: 23.94
+	Hs
		397873 ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69		EPIPL_HUMAN (3039-3941): 6.03e-42: 174: 27.75
+	Rn
		1144216 UBC_RAT (1-108): 1.27e-29: 127: 90.74		Q6XD99_RAT (1531-3190): 1.96e-15: 86.6: 9.24
+	Mm
		476949 UBC_MOUSE (1-108): 9.43e-30: 127: 90.74		DYST_MOUSE (4325-4624): 7.75e-09: 65: 17.00