HitPredict

Interactor 1: H2AV (P08985)
Histone H2A.v (H2A.F/Z) (H2A.Z)
Gene: His2Av

Interactor 2: H4 (P84040)
Histone H4
Gene: His4

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	27956707
Identification Methods	protein complementation assay
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	CENP-T_C~Histone, CENP-T_C~Histone_H2A_C
Common GO terms	GO:0000786 - nucleosome GO:0003677 - DNA binding GO:0005694 - chromosome GO:0030527 - structural constituent of chromatin GO:0046982 - protein heterodimerization activity
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 141 Dm			1 103
+	Hs
		591579 H2AX_HUMAN (5-141): 6.14e-60: 183: 57.04		H4_HUMAN (1-103): 1.72e-48: 151: 99.03
+	Hs
		418924 H2A1B_HUMAN (5-132): 3.14e-59: 181: 60.47		H4_HUMAN (1-103): 1.72e-48: 151: 99.03
+	Hs
		501953 H2AZ_HUMAN (1-122): 1.51e-59: 181: 98.36		H4_HUMAN (1-103): 1.72e-48: 151: 99.03
+	Hs
		502295 H2A1_HUMAN (5-132): 2.41e-59: 181: 60.47		H4_HUMAN (1-103): 1.72e-48: 151: 99.03
+	Hs
		634016 H2A1D_HUMAN (5-132): 2.66e-59: 181: 61.24		H4_HUMAN (1-103): 1.72e-48: 151: 99.03
+	Hs
		979828 H2A2A_HUMAN (5-132): 1.72e-59: 181: 61.24		H4_HUMAN (1-103): 1.72e-48: 151: 99.03
+	Hs
		979887 H2A3_HUMAN (5-132): 2.18e-59: 181: 61.24		H4_HUMAN (1-103): 1.72e-48: 151: 99.03
+	Hs
		980093 H2A1C_HUMAN (5-132): 1.83e-59: 181: 60.47		H4_HUMAN (1-103): 1.72e-48: 151: 99.03
+	Hs
		980176 H2A1A_HUMAN (5-133): 2.72e-59: 181: 59.23		H4_HUMAN (1-103): 1.72e-48: 151: 99.03
+	Hs
		980214 H2A1J_HUMAN (5-130): 2.44e-59: 181: 60.63		H4_HUMAN (1-103): 1.72e-48: 151: 99.03
+	Hs
		979876 H2AV_HUMAN (1-122): 6.84e-59: 180: 98.36		H4_HUMAN (1-103): 1.72e-48: 151: 99.03
+	Hs
		980152 H2A1H_HUMAN (5-130): 6.27e-59: 180: 60.63		H4_HUMAN (1-103): 1.72e-48: 151: 99.03
+	Hs
		979935 H2A2B_HUMAN (5-132): 8.5e-59: 179: 59.69		H4_HUMAN (1-103): 1.72e-48: 151: 99.03
+	Hs
		979742 H2A2C_HUMAN (5-131): 5.85e-58: 177: 60.94		H4_HUMAN (1-103): 1.72e-48: 151: 99.03
+	Hs
		980243 H2AJ_HUMAN (5-131): 1.03e-57: 177: 60.16		H4_HUMAN (1-103): 1.72e-48: 151: 99.03
+	Hs
		502105 H2AZ_HUMAN (1-122): 1.51e-59: 181: 98.36		H4G_HUMAN (1-98): 1.4e-38: 126: 83.67
+	Sc
		382435 H2AZ_YEAST (4-124): 2.78e-41: 135: 68.50		H4_YEAST (18-103): 5.88e-41: 132: 90.70