HitPredict

Interactor 1: PO2F2 (P09086)
POU domain, class 2, transcription factor 2 (Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2) (Octamer-binding protein 2) (Oct-2) (Octamer-binding transcription factor 2) (OTF-2)
Gene: POU2F2

Interactor 2: TLE4 (Q04727)
Transducin-like enhancer protein 4 (Grg-4) (Groucho-related protein 4)
Gene: TLE4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.561

Property	Details
Experiments	16103132
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 479 Hs			1 773
+	Hs
		814791 CUX1_HUMAN (8-440): 3.2e-45: 171: 16.95		TLE4_HUMAN (1-773): 0: 637: 100.00
+	Mm
		673999 PO2F1_MOUSE (58-409): 4.95e-39: 152: 55.46		TLE4_MOUSE (1-773): 0: 638: 99.61
+	Hs
		1047879 LHX3_HUMAN (286-470): 1.75e-38: 146: 22.12		TLE1_HUMAN (8-773): 0: 592: 86.27
+	Hs
		814790 CUX1_HUMAN (8-440): 3.2e-45: 171: 16.95		TLE3_HUMAN (8-773): 0: 556: 81.08
+	Hs
		1047880 HESX1_HUMAN (190-360): 6.01e-34: 127: 23.12		TLE1_HUMAN (8-773): 0: 592: 86.27
+	Hs
		877510 LHX1_HUMAN (266-465): 5.9e-13: 72.2: 24.03		TLE1_HUMAN (8-773): 0: 592: 86.27
+	Hs
		895705 LHX2_HUMAN (266-435): 1.16e-12: 71.4: 21.26		TLE1_HUMAN (8-773): 0: 592: 86.27
+	Dm
		594705 Q9NHP8_DROME (26-396): 2.24e-42: 159: 13.88		GROU_DROME (8-773): 5.4e-154: 467: 58.89
+	Hs
		1047981 ZFHX3_HUMAN (266-362): 3.85e-10: 64.7: 22.68		TLE3_HUMAN (8-773): 0: 556: 81.08
+	Mm
		629214 PO5F1_MOUSE (72-426): 7.99e-52: 181: 31.51		WDR5_MOUSE (525-771): 1.68e-85: 276: 17.72
+	Hs
		964861 PO5F1_HUMAN (113-426): 2.22e-47: 169: 32.91		WDR5_HUMAN (525-771): 1.68e-85: 276: 17.72
+	Mm
		673995 PO2F1_MOUSE (58-409): 4.95e-39: 152: 55.46		TLE5_MOUSE (8-205): 1.86e-93: 291: 67.68
+	Hs
		1061908 LHX3_HUMAN (286-470): 1.75e-38: 146: 22.12		TLE5_HUMAN (8-205): 2.2e-93: 291: 67.68
+	Hs
		895708 LHX2_HUMAN (266-435): 1.16e-12: 71.4: 21.26		TLE5_HUMAN (8-205): 2.2e-93: 291: 67.68
+	Hs
		1061710 ZFHX3_HUMAN (266-362): 3.85e-10: 64.7: 22.68		TLE5_HUMAN (8-205): 2.2e-93: 291: 67.68
+	Mm
		629219 PO5F1_MOUSE (72-426): 7.99e-52: 181: 31.51		GBB1_MOUSE (568-771): 1.49e-40: 154: 17.62
+	Ce
		629517 HM06_CAEEL (79-374): 2.6e-47: 169: 39.40		WDR51_CAEEL (696-772): 9.58e-19: 91: 23.08
+	Hs
		1155984 ZFHX3_HUMAN (266-362): 3.85e-10: 64.7: 22.68		SNR40_HUMAN (510-690): 4.17e-10: 64.3: 27.98