HitPredict

Interactor 1: MYL3 (P09542)
Myosin light chain 3 (Myosin alkali light chain 1, ventricular/slow skeletal muscle isoform) (Myosin light chain 1, slow-twitch muscle B/ventricular isoform) (MLC1SB)
Gene: MYL3

Interactor 2: MLRV (P51667)
Myosin regulatory light chain 2, ventricular/cardiac muscle isoform (MLC-2) (MLC-2v) (Myosin light chain 2, slow skeletal/ventricular muscle isoform) (MLC-2s/v)
Gene: Myl2

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29199018
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003785 - actin monomer binding GO:0005509 - calcium ion binding GO:0016459 - myosin complex GO:0031672 - A band GO:0055010 - ventricular cardiac muscle tissue morphogenesis and 1 others more... GO:0060048 - cardiac muscle contraction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 204 Mm			1 166
+	Hs
		169041 MYL1_HUMAN (43-203): 5.6e-66: 202: 75.16		ML12B_HUMAN (9-165): 7.59e-66: 200: 54.78
+	Hs
		437565 MYL1_HUMAN (43-203): 5.6e-66: 202: 75.16		ML12A_HUMAN (10-165): 1.12e-64: 197: 55.13
+	Hs
		169044 MYL4_HUMAN (46-203): 1.25e-57: 182: 83.54		ML12B_HUMAN (9-165): 7.59e-66: 200: 54.78
+	Hs
		169049 MYL6B_HUMAN (1-203): 1.88e-57: 181: 61.72		ML12B_HUMAN (9-165): 7.59e-66: 200: 54.78
+	Hs
		573921 MYL6B_HUMAN (1-203): 1.88e-57: 181: 61.72		ML12A_HUMAN (10-165): 1.12e-64: 197: 55.13
+	Hs
		573923 MYL6B_HUMAN (1-203): 1.88e-57: 181: 61.72		MYL9_HUMAN (10-165): 2.28e-64: 196: 54.49
+	Hs
		169075 MYL6_HUMAN (54-203): 1.3e-54: 172: 73.33		ML12B_HUMAN (9-165): 7.59e-66: 200: 54.78
+	Hs
		437557 MYL1_HUMAN (43-203): 5.6e-66: 202: 75.16		CALM1_HUMAN (10-89): 5.17e-10: 56.4: 25.30
+	Hs
		437558 MYL1_HUMAN (43-203): 5.6e-66: 202: 75.16		CALM3_HUMAN (10-89): 5.17e-10: 56.4: 25.30
+	At
		1182290 CDPK4_ARATH (7-203): 2.88e-56: 187: 21.72		CDPK4_ARATH (32-166): 2.63e-12: 65.3: 13.70
+	Gm
		1284629 Q84P28_SOYBN (7-203): 7.08e-54: 180: 20.20		Q84P28_SOYBN (34-166): 1.25e-14: 72.2: 12.50
+	At
		1057375 CDPK1_ARATH (7-201): 4.2e-55: 186: 21.43		CDPK1_ARATH (79-164): 2.32e-12: 65.6: 16.28
+	At
		1183276 CDPKB_ARATH (7-203): 8.67e-56: 185: 21.21		CDPKB_ARATH (92-166): 6.86e-12: 64.1: 16.67
+	At
		947591 CDPKU_ARATH (7-203): 4.52e-55: 184: 22.11		CALM7_ARATH (10-89): 2.47e-10: 57.6: 27.71
+	At
		515564 CDPKU_ARATH (7-203): 4.52e-55: 184: 22.11		CALM4_ARATH (10-89): 2.98e-10: 57.2: 27.71
+	At
		1043103 CDPKU_ARATH (7-203): 4.52e-55: 184: 22.11		CALM6_ARATH (10-89): 4.66e-10: 56.8: 27.71
+	Hs
		516305 MYL6B_HUMAN (1-203): 1.88e-57: 181: 61.72		CALM1_HUMAN (10-89): 5.17e-10: 56.4: 25.30
+	Hs
		516379 MYL6B_HUMAN (1-203): 1.88e-57: 181: 61.72		CALM2_HUMAN (10-89): 5.17e-10: 56.4: 25.30
+	Hs
		516461 MYL6B_HUMAN (1-203): 1.88e-57: 181: 61.72		CALM3_HUMAN (10-89): 5.17e-10: 56.4: 25.30
+	Hs
		516323 MYL6_HUMAN (54-203): 1.3e-54: 172: 73.33		CALM1_HUMAN (10-89): 5.17e-10: 56.4: 25.30