Interactor 1: FGFR1 (P11362)
Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331)
Gene: FGFR1
Interactor 2: FGFR1 (P11362)
Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331)
Gene: FGFR1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.96 | 1.00 | 0.984 |
The method score is based on:
Property | Details |
---|---|
Experiments | 19224897, 10464310, 8321198, 8752212, 21621521, 18022941, 28769084, 10830168, 26272615, 26300540, 1309784, 11030354, 31980649, 10918587, 8622701, 20133753, 19696444 |
Identification Methods | enzymatic study, pull down, x-ray crystallography, fluorescent resonance energy transfer, affinity chromatography technology, cross-linking study |
Interaction Type | direct interaction, association, physical association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | I-set~I-set, ig~I-set, ig~ig, PK_Tyr_Ser-Thr~PK_Tyr_Ser-Thr |
Common GO terms | GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000165 - MAPK cascade GO:0001501 - skeletal system development GO:0001525 - angiogenesis GO:0001657 - ureteric bud development and 77 others more... |
Homologous interactions | 16 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024