Interactor 1: FGFR1 (P11362)
Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331)
Gene: FGFR1

Interactor 2: FGFR1 (P11362)
Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331)
Gene: FGFR1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.984

The method score is based on:

Property Details
Experiments 19224897, 10464310, 8321198, 8752212, 21621521, 18022941, 28769084, 10830168, 26272615, 26300540, 1309784, 11030354, 31980649, 10918587, 8622701, 20133753, 19696444
Identification Methods enzymatic study, pull down, x-ray crystallography, fluorescent resonance energy transfer, affinity chromatography technology, cross-linking study
Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains I-set~I-set, ig~I-set, ig~ig, PK_Tyr_Ser-Thr~PK_Tyr_Ser-Thr
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000165 - MAPK cascade
GO:0001501 - skeletal system development
GO:0001525 - angiogenesis
GO:0001657 - ureteric bud development
and 77 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 822
Hs

1 822
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Last updated: 15 Jul 2024