HitPredict

Interactor 1: PABP1 (P11940)
Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1)
Gene: PABPC1

Interactor 2: NUCL (P19338)
Nucleolin (Protein C23)
Gene: NCL

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	20221403
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0016020 - membrane GO:0036464 - cytoplasmic ribonucleoprotein granule GO:0070062 - extracellular exosome and 1 others more... GO:1990904 - ribonucleoprotein complex
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 636 Hs			1 710
+	Hs
		516635 PABP1_HUMAN (1-636): 0: 582: 100.00		PABP5_HUMAN (233-555): 7.34e-51: 183: 17.20
+	Hs
		516339 PABP1_HUMAN (1-636): 0: 582: 100.00		PABP1_HUMAN (222-482): 4.4e-43: 167: 15.55
+	Hs
		516689 PABP1_HUMAN (1-636): 0: 582: 100.00		PABP3_HUMAN (221-482): 6.38e-43: 166: 16.20
+	Hs
		516495 PABP1_HUMAN (1-636): 0: 582: 100.00		PABP4_HUMAN (222-488): 1.86e-42: 165: 14.88
+	Hs
		474021 PABP4_HUMAN (1-635): 0: 534: 74.69		PAB4L_HUMAN (222-467): 8.2e-40: 152: 16.42
+	Hs
		1119141 PAP1L_HUMAN (1-628): 9.51e-166: 489: 68.20		PABP5_HUMAN (233-555): 7.34e-51: 183: 17.20
+	Sc
		376562 PABP_YEAST (2-335): 1.06e-64: 225: 26.71		PABP_YEAST (181-555): 3.61e-53: 194: 17.47
+	Hs
		582056 NUCL_HUMAN (3-89): 2.56e-19: 94.1: 33.33		NUCL_HUMAN (1-650): 8.84e-98: 318: 100.00
+	Zm
		8143 A0A1D6ELH4_MAIZE (2-467): 9.33e-68: 235: 25.36		A0A1D6ELH4_MAIZE (204-491): 4.85e-38: 152: 15.53
+	Sc
		376694 PABP_YEAST (2-335): 1.06e-64: 225: 26.71		PUB1_YEAST (475-648): 4.1e-16: 83.6: 28.89
+	Mm
		665745 TIA1_MOUSE (4-172): 1.01e-34: 137: 27.51		PABP1_MOUSE (222-482): 5.43e-43: 167: 15.55
+	Hs
		474034 PABP5_HUMAN (6-179): 5.04e-39: 149: 25.26		PAB4L_HUMAN (222-467): 8.2e-40: 152: 16.42