HitPredict

Interactor 1: A2RRC9 (A2RRC9)
IQ motif containing GTPase activating protein 3
Gene: IQGAP3

Interactor 2: B4DJ51 (B4DJ51)
Calmodulin 1 (Phosphorylase kinase, delta), isoform CRA_a (Calmodulin 3 (Phosphorylase kinase, delta), isoform CRA_b) (Epididymis secretory protein Li 72) (cDNA FLJ61744, highly similar to Calmodulin)
Gene: HEL-S-72

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.80	0.594

Property	Details
Experiments	25416956
Identification Methods	two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	CH~EF-hand_7, EF-hand_7~IQ
Common GO terms	-
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 1631 Hs			1 149
+	Hs
		516355 IQGA3_HUMAN (1-1631): 0: 1685: 99.82		CALM1_HUMAN (1-149): 4.29e-56: 174: 100.00
+	Hs
		516429 IQGA3_HUMAN (1-1631): 0: 1685: 99.82		CALM2_HUMAN (1-149): 4.29e-56: 174: 100.00
+	Hs
		516551 IQGA3_HUMAN (1-1631): 0: 1685: 99.82		CALM3_HUMAN (1-149): 4.29e-56: 174: 100.00
+	Hs
		516321 IQGA1_HUMAN (6-1631): 0: 1551: 59.05		CALM1_HUMAN (1-149): 4.29e-56: 174: 100.00
+	Hs
		516393 IQGA1_HUMAN (6-1631): 0: 1551: 59.05		CALM2_HUMAN (1-149): 4.29e-56: 174: 100.00
+	Hs
		516479 IQGA1_HUMAN (6-1631): 0: 1551: 59.05		CALM3_HUMAN (1-149): 4.29e-56: 174: 100.00
+	Hs
		692666 IQGA1_HUMAN (6-1631): 0: 1551: 59.05		CALL3_HUMAN (1-149): 4.36e-53: 166: 84.56
+	Hs
		692693 IQGA2_HUMAN (86-1631): 0: 1331: 42.50		CALL3_HUMAN (1-149): 4.36e-53: 166: 84.56
+	Hs
		516603 MYO5B_HUMAN (696-1522): 1.78e-100: 360: 13.71		CALM3_HUMAN (1-149): 4.29e-56: 174: 100.00
+	Dm
		52509 A1Z6Z9_DROME (699-1532): 6.06e-99: 355: 12.64		CALL_DROME (3-149): 2.69e-57: 177: 66.67
+	Dm
		52512 A1Z6Z9_DROME (699-1532): 6.06e-99: 355: 12.64		CALM_DROME (1-149): 1.07e-55: 173: 97.99
+	Hs
		516591 MYO5C_HUMAN (699-1480): 7.65e-92: 332: 12.59		CALM3_HUMAN (1-149): 4.29e-56: 174: 100.00
+	Hs
		516366 SYGP1_HUMAN (998-1345): 9.13e-66: 248: 16.34		CALM1_HUMAN (1-149): 4.29e-56: 174: 100.00
+	Sc
		449197 IQG1_YEAST (31-263): 6.92e-27: 122: 24.21		CALM_YEAST (1-75): 1.8e-14: 67.8: 40.79
+	Sp
		153415 IQG1_SCHPO (657-1020): 4.32e-25: 116: 18.13		CALM_SCHPO (73-149): 1.28e-14: 68.3: 40.26