Interactor 1: PCNA (P12004)
Proliferating cell nuclear antigen (PCNA) (Cyclin)
Gene: PCNA
Interactor 2: CDN1A (P38936)
Cyclin-dependent kinase inhibitor 1 (CDK-interacting protein 1) (Melanoma differentiation-associated protein 6) (MDA-6) (p21)
Gene: CDKN1A
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.99 | 0.60 | 0.772 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 23223023, 26186194, 26496610, 28514442, 11463845, 30217970, 29510343, 7915843, 8861969, 9545252, 11350925, 11313979, 17588519, 17115032, 19704162, 19895794, 11559705, 11254741, 21415862, 20605778 and 33 others
more... |
| Identification Methods | affinity chromatography technology, two hybrid, pull down, unspecified method, x-ray crystallography, coimmunoprecipitation, cosedimentation through density gradient, isothermal titration calorimetry, anti bait coimmunoprecipitation, two hybrid prey pooling approach and 9 others
more... |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0000307 - cyclin-dependent protein kinase holoenzyme complex GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0007507 - heart development GO:0016604 - nuclear body and 3 others more... |
| Homologous interactions | 6 |
Homologous interactions
Color coding for hit scores 
|
|
|||||||||||||
| + | Hs |   |
|
|||||||||||
| + | Mm | |
 |
|||||||||||
| + | Xl | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Xl | |
|
|||||||||||
| + | Dm | |
 |
|||||||||||
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
