HitPredict

Interactor 1: NOTCH (P07207)
Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein]
Gene: N

Interactor 2: DL (P10041)
Neurogenic locus protein delta
Gene: Delta

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.91 1.00 0.959

The method score is based on:

Property Details
Experiments 10935637, 23197537, 17923477, 18208612, 31722217, 2185893, 15611340, unassigned4
Identification Methods affinity chromatography technology, pull down, enzyme linked immunosorbent assay, experimental interaction detection
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains EGF~EGF, DL-JAG_EGF-like~EGF, EGF~hEGF, DSL~EGF_CA, EGF~EGF_CA, EGF_CA~hEGF, EGF_CA~MNNL, MNNL~hEGF
Common GO terms GO:0005509 - calcium ion binding
GO:0005768 - endosome
GO:0005769 - early endosome
GO:0005886 - plasma membrane
GO:0007015 - actin filament organization
and 30 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 2703
Dm

1 833
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Last updated: 11Aug2025