HitPredict

Interactor 1: ANDR (P10275)
Androgen receptor (Dihydrotestosterone receptor) (Nuclear receptor subfamily 3 group C member 4)
Gene: AR

Interactor 2: MRCKA (Q5VT25)
Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42-binding protein kinase alpha) (DMPK-like alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (MRCK alpha) (Myotonic dystrophy protein kinase-like alpha)
Gene: CDC42BPA

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	32814769
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0008270 - zinc ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 920 Hs			1 1732
+	Hs
		520130 ANDR_HUMAN (1-920): 0: 966: 100.00		MRCKG_HUMAN (4-1712): 0: 1155: 40.31
+	Hs
		396296 ESR1_HUMAN (378-904): 7.63e-136: 420: 22.20		MRCKA_HUMAN (1-1732): 0: 1630: 100.00
+	Hs
		397329 ESR1_HUMAN (378-904): 7.63e-136: 420: 22.20		MRCKB_HUMAN (1-1731): 0: 1429: 60.38
+	Hs
		1367697 ESR2_HUMAN (435-912): 2.49e-116: 367: 21.51		MRCKB_HUMAN (1-1731): 0: 1429: 60.38
+	Hs
		704563 RXRB_HUMAN (508-902): 1.59e-105: 339: 21.47		MRCKB_HUMAN (1-1731): 0: 1429: 60.38
+	Hs
		1231943 ESR2_HUMAN (435-912): 2.49e-116: 367: 21.51		MRCKG_HUMAN (4-1712): 0: 1155: 40.31
+	Hs
		519781 ANDR_HUMAN (1-920): 0: 966: 100.00		AKT1_HUMAN (13-407): 9.62e-129: 413: 31.02
+	Hs
		520399 ANDR_HUMAN (1-920): 0: 966: 100.00		LATS2_HUMAN (65-376): 3.55e-75: 275: 41.23
+	Hs
		156822 ESR1_HUMAN (378-904): 7.63e-136: 420: 22.20		CTRO_HUMAN (4-1022): 3.08e-130: 453: 24.42
+	Hs
		395573 ESR1_HUMAN (378-904): 7.63e-136: 420: 22.20		AKT2_HUMAN (13-391): 2.77e-129: 414: 30.65
+	Hs
		395572 ESR1_HUMAN (378-904): 7.63e-136: 420: 22.20		AKT1_HUMAN (13-407): 9.62e-129: 413: 31.02
+	Hs
		157694 ESR2_HUMAN (435-912): 2.49e-116: 367: 21.51		CTRO_HUMAN (4-1022): 3.08e-130: 453: 24.42
+	Hs
		403859 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		AKT1_HUMAN (13-407): 9.62e-129: 413: 31.02
+	Hs
		520522 RARA_HUMAN (460-902): 8.61e-110: 348: 19.87		AKT1_HUMAN (13-407): 9.62e-129: 413: 31.02
+	Hs
		665068 COT2_HUMAN (492-900): 2.14e-109: 345: 19.07		AKT2_HUMAN (13-391): 2.77e-129: 414: 30.65
+	Hs
		665067 COT2_HUMAN (492-900): 2.14e-109: 345: 19.07		AKT1_HUMAN (13-407): 9.62e-129: 413: 31.02
+	Hs
		652453 NR4A1_HUMAN (410-905): 1.86e-106: 343: 18.71		AKT1_HUMAN (13-407): 9.62e-129: 413: 31.02
+	Hs
		396152 ESR1_HUMAN (378-904): 7.63e-136: 420: 22.20		STK38_HUMAN (66-404): 1.25e-89: 302: 45.07
+	Hs
		287645 GCR_HUMAN (444-920): 1.2e-117: 378: 40.85		KS6A5_HUMAN (60-334): 2.61e-72: 261: 27.46
+	Mm
		542870 RARA_MOUSE (460-902): 4.85e-109: 346: 19.64		KS6A5_MOUSE (75-147): 3.33e-12: 73.7: 23.38