HitPredict

Interactor 1: KAP0 (P10644)
cAMP-dependent protein kinase type I-alpha regulatory subunit (Tissue-specific extinguisher 1) (TSE1)
Gene: PRKAR1A

Interactor 2: KAP3 (P31323)
cAMP-dependent protein kinase type II-beta regulatory subunit
Gene: PRKAR2B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.60 1.00 0.776

The method score is based on:

Property Details
Experiments 28514442, unassigned3799
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains cNMP_binding~cNMP_binding, RIIa~RIIa
Common GO terms GO:0004862 - cAMP-dependent protein kinase inhibitor activity
GO:0005737 - cytoplasm
GO:0005813 - centrosome
GO:0005829 - cytosol
GO:0005952 - cAMP-dependent protein kinase complex
and 10 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 381
Hs

1 418
+ Hs
+ Mm
+ Mm
+ Ce
+ Sp
+ Mm
+ Mm
+ Hs
+ Hs
+ Bt
+ Hs
+ Dm
+ Zm
+ Ce
+ Dm
+ Sc
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 11Aug2025