Interactor 1: KAP1 (P31321)
cAMP-dependent protein kinase type I-beta regulatory subunit
Gene: PRKAR1B
Interactor 2: KAP3 (P31323)
cAMP-dependent protein kinase type II-beta regulatory subunit
Gene: PRKAR2B
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.79 | 1.00 | 0.892 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 26186194, 28514442, 33961781, unassigned3799 |
| Identification Methods | affinity chromatography technology, anti tag coimmunoprecipitation |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | cNMP_binding~cNMP_binding, RIIa~RIIa |
| Common GO terms | GO:0004862 - cAMP-dependent protein kinase inhibitor activity GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005952 - cAMP-dependent protein kinase complex GO:0007189 - adenylate cyclase-activating G protein-coupled receptor signaling pathway and 6 others more... |
| Homologous interactions | 18 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
