HitPredict

Interactor 1: FGFR1 (P11362)
Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331)
Gene: FGFR1

Interactor 2: SEPT8 (Q92599)
Septin-8
Gene: SEPTIN8

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 822 Hs			1 483
+	Hs
		541728 FGFR1_HUMAN (1-822): 0: 858: 100.00		SEP10_HUMAN (1-429): 0: 586: 72.96
+	Hs
		541480 FGFR1_HUMAN (1-822): 0: 858: 100.00		SEPT6_HUMAN (1-429): 0: 580: 76.22
+	Hs
		541713 FGFR1_HUMAN (1-822): 0: 858: 100.00		SEP11_HUMAN (11-402): 0: 546: 81.12
+	Hs
		648611 FGFR4_HUMAN (31-813): 0: 660: 55.33		SEPT8_HUMAN (1-483): 0: 724: 100.00
+	Hs
		710872 EPHB2_HUMAN (4-819): 0: 637: 18.07		SEPT8_HUMAN (1-483): 0: 724: 100.00
+	Hs
		541655 FGFR1_HUMAN (1-822): 0: 858: 100.00		SEPT5_HUMAN (1-383): 8.98e-172: 489: 36.99
+	Hs
		541743 FGFR1_HUMAN (1-822): 0: 858: 100.00		SEPT9_HUMAN (8-319): 8.09e-157: 459: 39.81
+	Hs
		541741 FGFR1_HUMAN (1-822): 0: 858: 100.00		SEPT3_HUMAN (9-309): 1.89e-155: 447: 42.40
+	Hs
		648705 FGFR4_HUMAN (31-813): 0: 660: 55.33		SEP10_HUMAN (1-429): 0: 586: 72.96
+	Hs
		648508 FGFR4_HUMAN (31-813): 0: 660: 55.33		SEPT6_HUMAN (1-429): 0: 580: 76.22
+	Hs
		710908 EPHB2_HUMAN (4-819): 0: 637: 18.07		SEP10_HUMAN (1-429): 0: 586: 72.96
+	Hs
		710830 EPHB2_HUMAN (4-819): 0: 637: 18.07		SEPT6_HUMAN (1-429): 0: 580: 76.22
+	Hs
		931907 EPHA5_HUMAN (3-791): 0: 630: 18.90		SEP10_HUMAN (1-429): 0: 586: 72.96
+	Hs
		931850 EPHA5_HUMAN (3-791): 0: 630: 18.90		SEPT6_HUMAN (1-429): 0: 580: 76.22
+	Hs
		648699 FGFR4_HUMAN (31-813): 0: 660: 55.33		SEP11_HUMAN (11-402): 0: 546: 81.12
+	Hs
		648643 FGFR4_HUMAN (31-813): 0: 660: 55.33		SEPT5_HUMAN (1-383): 8.98e-172: 489: 36.99
+	Hs
		648716 FGFR4_HUMAN (31-813): 0: 660: 55.33		SEPT9_HUMAN (8-319): 8.09e-157: 459: 39.81
+	Hs
		648714 FGFR4_HUMAN (31-813): 0: 660: 55.33		SEPT3_HUMAN (9-309): 1.89e-155: 447: 42.40
+	Hs
		710912 EPHB2_HUMAN (4-819): 0: 637: 18.07		SEPT9_HUMAN (8-319): 8.09e-157: 459: 39.81
+	Hs
		710911 EPHB2_HUMAN (4-819): 0: 637: 18.07		SEPT3_HUMAN (9-309): 1.89e-155: 447: 42.40