HitPredict

Interactor 1: FGFR1 (P11362)
Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331)
Gene: FGFR1

Interactor 2: E41LA (Q9HCS5)
Band 4.1-like protein 4A (Erythrocyte membrane protein band 4.1-like 4A) (Protein NBL4)
Gene: EPB41L4A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.80	0.618

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	FERM_M~PK_Tyr_Ser-Thr
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 822 Hs			1 686
+	Hs
		541777 FGFR1_HUMAN (1-822): 0: 858: 100.00		FARP1_HUMAN (9-429): 1.99e-119: 383: 26.48
+	Hs
		541312 FGFR1_HUMAN (1-822): 0: 858: 100.00		EZRI_HUMAN (7-552): 1.97e-116: 363: 18.94
+	Hs
		541349 FGFR1_HUMAN (1-822): 0: 858: 100.00		MOES_HUMAN (7-555): 4.92e-113: 353: 18.00
+	Hs
		541368 FGFR1_HUMAN (1-822): 0: 858: 100.00		MERL_HUMAN (6-570): 1.29e-111: 350: 20.10
+	Hs
		710506 EPHA2_HUMAN (3-819): 0: 583: 18.48		E41LA_HUMAN (1-686): 0: 575: 100.00
+	Hs
		538874 FGFR3_HUMAN (6-821): 0: 727: 61.22		EPB41_HUMAN (9-675): 1.73e-126: 397: 24.78
+	Hs
		320534 FGFR3_HUMAN (6-821): 0: 727: 61.22		FARP2_HUMAN (8-560): 2.17e-123: 394: 24.96
+	Hs
		582664 FGFR4_HUMAN (31-813): 0: 660: 55.33		EZRI_HUMAN (7-552): 1.97e-116: 363: 18.94
+	Hs
		710493 EPHA2_HUMAN (3-819): 0: 583: 18.48		E41L1_HUMAN (9-665): 9.74e-142: 437: 25.48
+	Hs
		648424 FGFR4_HUMAN (31-813): 0: 660: 55.33		MOES_HUMAN (7-555): 4.92e-113: 353: 18.00
+	Hs
		648441 FGFR4_HUMAN (31-813): 0: 660: 55.33		MERL_HUMAN (6-570): 1.29e-111: 350: 20.10
+	Hs
		710487 EPHA2_HUMAN (3-819): 0: 583: 18.48		E41LB_HUMAN (6-610): 3.32e-131: 410: 26.85
+	Hs
		683779 EPHB2_HUMAN (4-819): 0: 637: 18.07		MOES_HUMAN (7-555): 4.92e-113: 353: 18.00
+	Hs
		710785 EPHB2_HUMAN (4-819): 0: 637: 18.07		MERL_HUMAN (6-570): 1.29e-111: 350: 20.10
+	Hs
		320536 EPHA2_HUMAN (3-819): 0: 583: 18.48		FARP2_HUMAN (8-560): 2.17e-123: 394: 24.96
+	Hs
		710505 EPHA2_HUMAN (3-819): 0: 583: 18.48		E41L5_HUMAN (8-414): 2.3e-126: 393: 37.23
+	Hs
		710261 EPHA2_HUMAN (3-819): 0: 583: 18.48		PTN14_HUMAN (11-686): 3.2e-120: 388: 19.83
+	Hs
		217389 EPHA2_HUMAN (3-819): 0: 583: 18.48		E41L2_HUMAN (8-635): 1.99e-121: 387: 23.56
+	Hs
		582679 EPHA2_HUMAN (3-819): 0: 583: 18.48		EZRI_HUMAN (7-552): 1.97e-116: 363: 18.94
+	Hs
		710096 EPHA2_HUMAN (3-819): 0: 583: 18.48		MERL_HUMAN (6-570): 1.29e-111: 350: 20.10