HitPredict

Interactor 1: RAC2 (P15153)
Ras-related C3 botulinum toxin substrate 2 (GX) (Small G protein) (p21-Rac2)
Gene: RAC2

Interactor 2: ELMO2 (Q96JJ3)
Engulfment and cell motility protein 2 (Protein ced-12 homolog A) (hCed-12A)
Gene: ELMO2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	PH_12~Ras
Common GO terms	GO:0005829 - cytosol GO:0007015 - actin filament organization
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 192 Hs			1 720
+	Hs
		925522 RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19		ELMO2_HUMAN (1-720): 0: 1053: 100.00
+	Hs
		951239 RHOG_HUMAN (1-192): 1.64e-77: 231: 70.83		ELMO2_HUMAN (1-720): 0: 1053: 100.00
+	Hs
		925482 RAC1_HUMAN (1-192): 1.69e-84: 249: 92.19		ELMO1_HUMAN (1-718): 0: 1012: 75.48
+	Hs
		951196 RHOG_HUMAN (1-192): 1.64e-77: 231: 70.83		ELMO1_HUMAN (1-718): 0: 1012: 75.48
+	Hs
		545552 RAC2_HUMAN (1-192): 3.42e-82: 243: 100.00		ELMO3_HUMAN (1-718): 0: 944: 50.49
+	Ce
		104470 G5EBV3_CAEEL (2-192): 1.3e-77: 231: 62.30		CED12_CAEEL (27-713): 0: 673: 21.49
+	Hs
		951143 RHOG_HUMAN (1-192): 1.64e-77: 231: 70.83		ELMD2_HUMAN (285-485): 2.58e-51: 182: 18.32
+	Hs
		900680 RHOA_HUMAN (5-192): 9.29e-76: 227: 54.26		ELMD1_HUMAN (297-486): 2.25e-47: 172: 15.28