HitPredict

Interactor 1: EZRI (P15311)
Ezrin (Cytovillin) (Villin-2) (p81)
Gene: EZR

Interactor 2: CRACD (Q6ZU35)
Capping protein-inhibiting regulator of actin dynamics (Cancer-related regulator of actin dynamics)
Gene: CRACD

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	29568061, 34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 586 Hs			1 1233
+	Hs
		719738 RADI_HUMAN (1-586): 7.83e-165: 484: 76.28		CRACD_HUMAN (1-1233): 0: 570: 100.00
+	Hs
		547074 EZRI_HUMAN (1-586): 5.67e-178: 517: 100.00		ITSN1_HUMAN (163-511): 8.51e-29: 127: 17.71
+	Hs
		547271 EZRI_HUMAN (1-586): 5.67e-178: 517: 100.00		MYH13_HUMAN (204-760): 2.94e-15: 83.5: 11.88
+	Hs
		546914 EZRI_HUMAN (1-586): 5.67e-178: 517: 100.00		EZRI_HUMAN (224-457): 3.3e-11: 69.5: 21.25
+	Hs
		547232 EZRI_HUMAN (1-586): 5.67e-178: 517: 100.00		MYO5C_HUMAN (265-545): 5.44e-10: 66.1: 14.39
+	Hs
		640146 MOES_HUMAN (1-586): 4.45e-161: 474: 72.70		CP250_HUMAN (109-757): 1.05e-22: 108: 10.54
+	Hs
		148355 EZRI_HUMAN (1-586): 5.67e-178: 517: 100.00		CTRO_HUMAN (90-532): 2.83e-09: 64.1: 20.27
+	Hs
		640054 MOES_HUMAN (1-586): 4.45e-161: 474: 72.70		MYH9_HUMAN (135-826): 1.43e-22: 107: 10.92
+	Hs
		546955 RADI_HUMAN (1-586): 7.83e-165: 484: 76.28		EZRI_HUMAN (224-457): 3.3e-11: 69.5: 21.25
+	Hs
		505632 EPB41_HUMAN (3-553): 9.55e-129: 400: 22.99		DCTN1_HUMAN (83-539): 1.36e-36: 152: 19.62
+	Hs
		546934 MOES_HUMAN (1-586): 4.45e-161: 474: 72.70		EZRI_HUMAN (224-457): 3.3e-11: 69.5: 21.25
+	Hs
		505569 EPB41_HUMAN (3-553): 9.55e-129: 400: 22.99		MYH10_HUMAN (149-782): 1.39e-23: 110: 9.39
+	Hs
		505568 EPB41_HUMAN (3-553): 9.55e-129: 400: 22.99		MYH9_HUMAN (135-826): 1.43e-22: 107: 10.92
+	Hs
		546954 MERL_HUMAN (2-586): 3.18e-146: 436: 44.37		EZRI_HUMAN (224-457): 3.3e-11: 69.5: 21.25
+	Hs
		148455 MERL_HUMAN (2-586): 3.18e-146: 436: 44.37		CTRO_HUMAN (90-532): 2.83e-09: 64.1: 20.27
+	Hs
		547226 E41L5_HUMAN (5-586): 7.7e-142: 430: 21.28		EZRI_HUMAN (224-457): 3.3e-11: 69.5: 21.25
+	Hs
		505545 EPB41_HUMAN (3-553): 9.55e-129: 400: 22.99		EZRI_HUMAN (224-457): 3.3e-11: 69.5: 21.25
+	Hs
		505542 EPB41_HUMAN (3-553): 9.55e-129: 400: 22.99		MYH1_HUMAN (340-800): 5.66e-10: 66.2: 9.89
+	Hs
		505634 EPB41_HUMAN (3-553): 9.55e-129: 400: 22.99		NUMA1_HUMAN (354-775): 5.31e-10: 66.2: 10.75
+	Hs
		547217 E41L1_HUMAN (3-524): 3.54e-119: 375: 23.06		EZRI_HUMAN (224-457): 3.3e-11: 69.5: 21.25