HitPredict

Interactor 1: HS90B (P11499)
Heat shock protein HSP 90-beta (Heat shock 84 kDa) (HSP 84) (HSP84) (Tumor-specific transplantation 84 kDa antigen) (TSTA)
Gene: Hsp90ab1

Interactor 2: Q80SY9 (Q80SY9)
Nucleotide-binding oligomerization domain-containing protein 2
Gene: Nod2

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	23019338
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0019901 - protein kinase binding GO:0032991 - protein-containing complex
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 724 Mm			1 1013
+	Hs
		461325 HS90A_HUMAN (1-724): 0: 1066: 85.66		NAL12_HUMAN (191-1010): 4.35e-143: 456: 21.27
+	Hs
		461980 HS90A_HUMAN (1-724): 0: 1066: 85.66		NALP2_HUMAN (208-1013): 2.23e-110: 368: 18.71
+	Hs
		573411 ENPL_HUMAN (3-696): 0: 912: 46.38		NLRP6_HUMAN (191-948): 2.23e-101: 340: 19.90
+	Hs
		468538 HS90B_HUMAN (1-724): 0: 1080: 99.59		NLRC3_HUMAN (521-927): 2.44e-30: 131: 19.45
+	Hs
		461825 HS90A_HUMAN (1-724): 0: 1066: 85.66		NALP4_HUMAN (610-987): 2.17e-33: 141: 20.77
+	Hs
		461645 HS90A_HUMAN (1-724): 0: 1066: 85.66		NLRC3_HUMAN (521-927): 2.44e-30: 131: 19.45
+	Mm
		547269 HS90B_MOUSE (1-724): 0: 1083: 100.00		NOD1_MOUSE (711-923): 1.64e-21: 103: 20.00
+	Hs
		461828 HS90A_HUMAN (1-724): 0: 1066: 85.66		NLRP3_HUMAN (569-932): 4.26e-26: 118: 17.91
+	Hs
		462057 HS90A_HUMAN (1-724): 0: 1066: 85.66		NOD1_HUMAN (843-1009): 3.47e-24: 111: 29.94
+	Mm
		462134 HS90A_MOUSE (1-724): 0: 1062: 84.72		NOD1_MOUSE (711-923): 1.64e-21: 103: 20.00
+	Hs
		468307 HS90B_HUMAN (1-724): 0: 1080: 99.59		LR74A_HUMAN (587-874): 1.71e-12: 72.8: 15.05
+	Hs
		947356 Q6PK50_HUMAN (1-350): 0: 616: 99.43		NAL12_HUMAN (191-1010): 4.35e-143: 456: 21.27
+	Hs
		573547 ENPL_HUMAN (3-696): 0: 912: 46.38		NLRC3_HUMAN (521-927): 2.44e-30: 131: 19.45
+	Hs
		1245586 Q6PK50_HUMAN (1-350): 0: 616: 99.43		NOD1_HUMAN (843-1009): 3.47e-24: 111: 29.94