Interactor 1: DESP (P15924)
Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen)
Gene: DSP

Interactor 2: PKP1 (Q13835)
Plakophilin-1 (Band 6 protein) (B6P)
Gene: PKP1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.67 0.60 0.634

The method score is based on:

Property Details
Experiments 24981860, 10852826
Identification Methods affinity chromatography technology, pull down, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001533 - cornified envelope
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005882 - intermediate filament
GO:0005886 - plasma membrane
and 4 others

more...

Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 2871
Hs

1 747
+ Hs
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+ Hs
+ Hs
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+ Dm
+ Rn
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+ Hs

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Last updated: 15 Jul 2024