HitPredict

Interactor 1: PGFRA (P16234)
Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha platelet-derived growth factor receptor) (Alpha-type platelet-derived growth factor receptor) (CD140 antigen-like family member A) (CD140a antigen) (Platelet-derived growth factor alpha receptor) (Platelet-derived growth factor receptor 2) (PDGFR-2) (CD antigen CD140a)
Gene: PDGFRA

Interactor 2: LOXL2 (Q9Y4K0)
Lysyl oxidase homolog 2 (EC 1.4.3.13) (Lysyl oxidase-like protein 2) (Lysyl oxidase-related protein 2) (Lysyl oxidase-related protein WS9-14)
Gene: LOXL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016020 - membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1089 Hs			1 774
+	Hs
		557081 PGFRA_HUMAN (1-1089): 0: 817: 100.00		NETR_HUMAN (28-200): 1.62e-35: 146: 32.20
+	Hs
		609481 FGFR3_HUMAN (745-969): 1.84e-76: 270: 40.74		LOXL4_HUMAN (6-438): 6.86e-62: 223: 21.49
+	Hs
		601503 FGFR2_HUMAN (6-339): 9.02e-49: 189: 14.90		LG3BP_HUMAN (197-302): 9.32e-30: 127: 22.64
+	Hs
		729268 VGFR3_HUMAN (128-609): 7.49e-19: 94.9: 11.28		LG3BP_HUMAN (197-302): 9.32e-30: 127: 22.64
+	Mm
		672764 MERTK_MOUSE (18-214): 2.53e-15: 83.4: 14.62		MSRE_MOUSE (161-303): 3.7e-33: 135: 18.88
+	Hs
		674406 UFO_HUMAN (13-225): 2.38e-15: 83.4: 14.71		LG3BP_HUMAN (197-302): 9.32e-30: 127: 22.64
+	Hs
		995373 NTRK3_HUMAN (28-227): 3.23e-13: 76.1: 9.01		LG3BP_HUMAN (197-302): 9.32e-30: 127: 22.64
+	Hs
		169172 MUSK_HUMAN (2-127): 4.82e-12: 72.6: 12.98		LG3BP_HUMAN (197-302): 9.32e-30: 127: 22.64