HitPredict

Interactor 1: PP2BB (P16298)
Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform (EC 3.1.3.16) (CAM-PRP catalytic subunit) (Calmodulin-dependent calcineurin A subunit beta isoform) (CNA beta)
Gene: PPP3CB

Interactor 2: RCAN2 (Q14206)
Calcipressin-2 (Down syndrome candidate region 1-like 1) (Myocyte-enriched calcineurin-interacting protein 2) (MCIP2) (Regulator of calcineurin 2) (Thyroid hormone-responsive protein ZAKI-4)
Gene: RCAN2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 524 Hs			1 197
+	Hs
		994080 PP2BA_HUMAN (13-523): 0: 843: 83.20		RCAN2_HUMAN (1-197): 2.21e-113: 322: 100.00
+	Hs
		557578 PP2BB_HUMAN (22-524): 0: 870: 100.00		RCAN3_HUMAN (6-197): 1.5e-101: 294: 68.23
+	Hs
		557530 PP2BB_HUMAN (22-524): 0: 870: 100.00		RCAN1_HUMAN (1-193): 1.19e-97: 285: 60.91
+	Hs
		994121 PP2BA_HUMAN (13-523): 0: 843: 83.20		RCAN3_HUMAN (6-197): 1.5e-101: 294: 68.23
+	Hs
		819151 PP2BC_HUMAN (20-516): 0: 810: 82.33		RCAN2_HUMAN (1-197): 2.21e-113: 322: 100.00
+	Hs
		865104 PP2BA_HUMAN (13-523): 0: 843: 83.20		RCAN1_HUMAN (1-193): 1.19e-97: 285: 60.91
+	Hs
		819181 PP2BC_HUMAN (20-516): 0: 810: 82.33		RCAN3_HUMAN (6-197): 1.5e-101: 294: 68.23
+	Hs
		819141 PP2BC_HUMAN (20-516): 0: 810: 82.33		RCAN1_HUMAN (1-193): 1.19e-97: 285: 60.91
+	Dm
		1375383 PP2B3_DROME (11-508): 0: 780: 76.59		SRA_DROME (3-190): 2.62e-80: 242: 43.39
+	Dm
		1099957 PP2B2_DROME (22-520): 0: 773: 76.49		SRA_DROME (3-190): 2.62e-80: 242: 43.39
+	Ce
		865127 PP2B_CAEEL (23-503): 0: 747: 74.95		RCANL_CAEEL (5-181): 2.16e-81: 242: 39.23