HitPredict

Interactor 1: H12 (P16403)
Histone H1.2 (Histone H1c) (Histone H1d) (Histone H1s-1)
Gene: H1-2

Interactor 2: H2B2E (Q16778)
Histone H2B type 2-E (H2B-clustered histone 21) (Histone H2B-GL105) (Histone H2B.q) (H2B/q)
Gene: H2BC21

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.621

Property	Details
Experiments	30021884, 35271311
Identification Methods	proximity labelling technology, affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000786 - nucleosome GO:0005634 - nucleus GO:0006334 - nucleosome assembly GO:0030527 - structural constituent of chromatin
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 213 Hs			1 126
+	Hs
		559369 H13_HUMAN (1-181): 4.78e-25: 99.5: 82.42		H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21
+	Hs
		559420 H13_HUMAN (1-181): 4.78e-25: 99.5: 82.42		H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00
+	Hs
		559462 H13_HUMAN (1-181): 4.78e-25: 99.5: 82.42		H2B1H_HUMAN (1-126): 6.27e-54: 166: 98.41
+	Hs
		241437 H13_HUMAN (1-181): 4.78e-25: 99.5: 82.42		H2B1K_HUMAN (1-126): 1.56e-53: 165: 98.41
+	Hs
		559361 H13_HUMAN (1-181): 4.78e-25: 99.5: 82.42		H2B1D_HUMAN (1-126): 3.5e-53: 164: 98.41
+	Hs
		608521 H1T_HUMAN (1-183): 5.25e-24: 96.4: 53.40		H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21
+	Hs
		608563 H1T_HUMAN (1-183): 5.25e-24: 96.4: 53.40		H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00
+	Hs
		608605 H1T_HUMAN (1-183): 5.25e-24: 96.4: 53.40		H2B1H_HUMAN (1-126): 6.27e-54: 166: 98.41
+	Hs
		608619 H1T_HUMAN (1-183): 5.25e-24: 96.4: 53.40		H2B1M_HUMAN (1-126): 5.38e-54: 166: 96.03
+	Hs
		559479 H13_HUMAN (1-181): 4.78e-25: 99.5: 82.42		H2B1L_HUMAN (1-126): 2.49e-52: 162: 97.62
+	Hs
		241447 H1T_HUMAN (1-183): 5.25e-24: 96.4: 53.40		H2B1K_HUMAN (1-126): 1.56e-53: 165: 98.41
+	Hs
		559747 H12_HUMAN (1-173): 1.53e-22: 92.6: 100.00		H2B2F_HUMAN (1-126): 2.34e-54: 168: 97.62
+	Hs
		608618 H1T_HUMAN (1-183): 5.25e-24: 96.4: 53.40		H2B1N_HUMAN (1-126): 3.35e-53: 164: 98.41
+	Hs
		559635 H12_HUMAN (1-173): 1.53e-22: 92.6: 100.00		H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21
+	Hs
		241438 H12_HUMAN (1-173): 1.53e-22: 92.6: 100.00		H2B1K_HUMAN (1-126): 1.56e-53: 165: 98.41
+	Hs
		559576 H12_HUMAN (1-173): 1.53e-22: 92.6: 100.00		H2B1B_HUMAN (1-126): 1.74e-53: 165: 98.41
+	Hs
		608586 H1T_HUMAN (1-183): 5.25e-24: 96.4: 53.40		H2B3B_HUMAN (1-126): 1.01e-51: 161: 96.03
+	Hs
		559622 H12_HUMAN (1-173): 1.53e-22: 92.6: 100.00		H2B1D_HUMAN (1-126): 3.5e-53: 164: 98.41
+	Hs
		608607 H1T_HUMAN (1-183): 5.25e-24: 96.4: 53.40		H2B1A_HUMAN (1-126): 3.43e-46: 147: 85.04
+	Hs
		559764 H12_HUMAN (1-173): 1.53e-22: 92.6: 100.00		H2B2C_HUMAN (1-96): 1.25e-43: 143: 91.67