HitPredict

Interactor 1: RHOQ (P17081)
Rho-related GTP-binding protein RhoQ (Ras-like protein TC10) (Ras-like protein family member 7A)
Gene: RHOQ

Interactor 2: MERL (P35240)
Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomerlin) (Schwannomin)
Gene: NF2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	FERM_M~Ras
Common GO terms	GO:0005886 - plasma membrane GO:0008360 - regulation of cell shape
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 205 Hs			1 595
+	Hs
		719617 RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59		MERL_HUMAN (1-595): 1.12e-172: 504: 100.00
+	Hs
		719446 RHOG_HUMAN (9-199): 2.46e-81: 241: 54.97		MERL_HUMAN (1-595): 1.12e-172: 504: 100.00
+	Hs
		719441 RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98		MERL_HUMAN (1-595): 1.12e-172: 504: 100.00
+	Hs
		1330927 RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59		E41L5_HUMAN (2-595): 6.77e-134: 410: 18.38
+	Hs
		1330914 RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59		E41L1_HUMAN (1-535): 3.42e-120: 378: 21.61
+	Hs
		547002 RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98		EZRI_HUMAN (19-595): 8.21e-152: 450: 44.20
+	Hs
		719697 RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98		RADI_HUMAN (19-595): 5.41e-151: 448: 45.47
+	Hs
		1331006 RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59		FARP1_HUMAN (2-526): 5.38e-114: 366: 18.35
+	Hs
		1330999 RHOJ_HUMAN (9-204): 1.17e-108: 311: 79.59		E41L3_HUMAN (14-484): 8.79e-113: 363: 21.04
+	Hs
		564694 RHOQ_HUMAN (1-205): 2.78e-83: 247: 100.00		E41L5_HUMAN (2-595): 6.77e-134: 410: 18.38
+	Hs
		951359 RHOG_HUMAN (9-199): 2.46e-81: 241: 54.97		E41L5_HUMAN (2-595): 6.77e-134: 410: 18.38
+	Hs
		505620 RHOG_HUMAN (9-199): 2.46e-81: 241: 54.97		EPB41_HUMAN (3-566): 9.71e-126: 392: 19.73
+	Hs
		564684 RHOQ_HUMAN (1-205): 2.78e-83: 247: 100.00		E41L1_HUMAN (1-535): 3.42e-120: 378: 21.61
+	Hs
		925608 RAC1_HUMAN (10-195): 4.15e-80: 238: 63.98		E41LB_HUMAN (1-572): 1.61e-121: 382: 17.03
+	Hs
		951337 RHOG_HUMAN (9-199): 2.46e-81: 241: 54.97		E41L1_HUMAN (1-535): 3.42e-120: 378: 21.61
+	Hs
		564756 RHOQ_HUMAN (1-205): 2.78e-83: 247: 100.00		FARP1_HUMAN (2-526): 5.38e-114: 366: 18.35
+	Hs
		564749 RHOQ_HUMAN (1-205): 2.78e-83: 247: 100.00		E41L3_HUMAN (14-484): 8.79e-113: 363: 21.04
+	Hs
		951489 RHOG_HUMAN (9-199): 2.46e-81: 241: 54.97		FARP1_HUMAN (2-526): 5.38e-114: 366: 18.35
+	Hs
		951471 RHOG_HUMAN (9-199): 2.46e-81: 241: 54.97		E41L3_HUMAN (14-484): 8.79e-113: 363: 21.04
+	Mm
		250712 RAC1_MOUSE (10-195): 4.15e-80: 238: 63.98		E41L2_MOUSE (10-519): 5.29e-114: 364: 20.68