HitPredict

Interactor 1: PRG2 (P13727)
Bone marrow proteoglycan (BMPG) (Proteoglycan 2) [Cleaved into: Eosinophil granule major basic protein (EMBP) (MBP) (Pregnancy-associated major basic protein)]
Gene: PRG2

Interactor 2: LTBP2 (Q14767)
Latent-transforming growth factor beta-binding protein 2 (LTBP-2)
Gene: LTBP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	EGF~Lectin_C
Common GO terms	GO:0005576 - extracellular region GO:0008201 - heparin binding GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 222 Hs			1 1821
+	Hs
		1132153 PRG3_HUMAN (12-222): 1.53e-53: 173: 49.30		LTBP2_HUMAN (1-1821): 0: 696: 100.00
+	Hs
		567812 PRG2_HUMAN (1-222): 1.94e-56: 180: 100.00		NOTC1_HUMAN (172-1495): 1.28e-82: 305: 15.09
+	Hs
		565088 CSPG2_HUMAN (4-221): 1.68e-45: 163: 17.00		FBN1_HUMAN (648-1820): 1.81e-64: 246: 20.05
+	Hs
		567906 PRG2_HUMAN (1-222): 1.94e-56: 180: 100.00		FRAS1_HUMAN (373-1351): 7.93e-41: 168: 13.24
+	Hs
		567807 PRG2_HUMAN (1-222): 1.94e-56: 180: 100.00		FBN2_HUMAN (274-1116): 2.17e-40: 167: 16.38
+	Hs
		1294398 PRG3_HUMAN (12-222): 1.53e-53: 173: 49.30		FRAS1_HUMAN (373-1351): 7.93e-41: 168: 13.24
+	Hs
		772351 PRG3_HUMAN (12-222): 1.53e-53: 173: 49.30		FBN2_HUMAN (274-1116): 2.17e-40: 167: 16.38
+	Hs
		567836 PRG2_HUMAN (1-222): 1.94e-56: 180: 100.00		NOTC2_HUMAN (1225-1821): 1.55e-35: 151: 13.10
+	Hs
		1047786 PRG3_HUMAN (12-222): 1.53e-53: 173: 49.30		NOTC2_HUMAN (1225-1821): 1.55e-35: 151: 13.10
+	Hs
		446107 FCER2_HUMAN (5-220): 1.84e-50: 168: 20.08		NOTC2_HUMAN (1225-1821): 1.55e-35: 151: 13.10
+	Hs
		567916 PRG2_HUMAN (1-222): 1.94e-56: 180: 100.00		LTBP4_HUMAN (149-1263): 3.18e-29: 130: 12.98
+	Hs
		568017 PRG2_HUMAN (1-222): 1.94e-56: 180: 100.00		NOTC3_HUMAN (98-844): 3.27e-22: 107: 9.70
+	Hs
		1392401 PGCB_HUMAN (10-221): 6.77e-53: 184: 17.20		JAG2_HUMAN (151-774): 6.03e-20: 99.5: 11.64
+	Hs
		568022 PRG2_HUMAN (1-222): 1.94e-56: 180: 100.00		JAG2_HUMAN (151-774): 6.03e-20: 99.5: 11.64
+	Hs
		1022269 PGCB_HUMAN (10-221): 6.77e-53: 184: 17.20		FBLN2_HUMAN (1134-1553): 8.34e-18: 92.4: 28.44
+	Hs
		567993 PRG2_HUMAN (1-222): 1.94e-56: 180: 100.00		LTBP3_HUMAN (3-834): 1.11e-15: 85.6: 8.69
+	Hs
		158528 NCAN_HUMAN (16-221): 7.19e-45: 161: 16.80		TENA_HUMAN (1527-1819): 2.97e-20: 100: 12.38
+	Hs
		565099 CSPG2_HUMAN (4-221): 1.68e-45: 163: 17.00		FBLN2_HUMAN (1134-1553): 8.34e-18: 92.4: 28.44
+	Hs
		567989 PRG2_HUMAN (1-222): 1.94e-56: 180: 100.00		CELR2_HUMAN (1614-1820): 7.67e-09: 63.2: 10.05
+	Mm
		1228174 FREM1_MOUSE (31-221): 6.48e-35: 132: 17.95		FRAS1_MOUSE (186-863): 1.99e-17: 91.8: 9.04