HitPredict

Interactor 1: PTN1 (P18031)
Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B)
Gene: PTPN1

Interactor 2: RAB5C (P51148)
Ras-related protein Rab-5C (EC 3.6.5.2) (L1880) (RAB5L)
Gene: RAB5C

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.50	0.533

Property	Details
Experiments	27432908, 34079125
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 435 Hs			1 216
+	Hs
		573565 PTN1_HUMAN (1-435): 0: 539: 100.00		RAB5A_HUMAN (1-216): 1.03e-89: 264: 86.57
+	Hs
		573653 PTN1_HUMAN (1-435): 0: 539: 100.00		RB11A_HUMAN (12-216): 7.61e-88: 259: 39.25
+	Hs
		914038 PTPRJ_HUMAN (2-301): 3.29e-123: 389: 33.44		RB11A_HUMAN (12-216): 7.61e-88: 259: 39.25
+	Hs
		592218 PTN12_HUMAN (24-314): 1e-122: 376: 33.55		RAB5A_HUMAN (1-216): 1.03e-89: 264: 86.57
+	Hs
		489922 PTPRF_HUMAN (19-278): 2.99e-105: 344: 30.94		RAB5C_HUMAN (1-216): 3.2e-94: 275: 100.00
+	Hs
		914025 PTN11_HUMAN (39-274): 7.78e-49: 177: 38.80		RB11A_HUMAN (12-216): 7.61e-88: 259: 39.25