HitPredict

Interactor 1: RCC1 (P18754)
Regulator of chromosome condensation (Cell cycle regulatory protein) (Chromosome condensation protein 1)
Gene: RCC1

Interactor 2: H2B2E (Q16778)
Histone H2B type 2-E (H2B-clustered histone 21) (Histone H2B-GL105) (Histone H2B.q) (H2B/q)
Gene: H2BC21

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.63	0.60	0.619

Property	Details
Experiments	35271311, 20347844
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0046982 - protein heterodimerization activity
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 421 Hs			1 126
+	Hs
		578411 RCC1_HUMAN (1-421): 5.38e-164: 469: 100.00		H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21
+	Hs
		886113 HERC1_HUMAN (255-419): 7.49e-34: 136: 26.47		H2B1D_HUMAN (1-126): 3.5e-53: 164: 98.41
+	Hs
		1078052 HERC1_HUMAN (255-419): 7.49e-34: 136: 26.47		H2B1L_HUMAN (1-126): 2.49e-52: 162: 97.62
+	Hs
		918743 RCC2_HUMAN (1-190): 1.36e-18: 89.7: 18.84		H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21
+	Sc
		355776 RCC1_YEAST (192-419): 1.22e-30: 124: 18.85		H2B2_YEAST (3-125): 4.73e-37: 124: 71.55
+	Sc
		355346 RCC1_YEAST (192-419): 1.22e-30: 124: 18.85		H2B1_YEAST (3-125): 1.81e-36: 122: 71.55