HitPredict

Interactor 1: RAC2 (P15153)
Ras-related C3 botulinum toxin substrate 2 (EC 3.6.5.2) (GX) (Small G protein) (p21-Rac2)
Gene: RAC2

Interactor 2: DIAP3 (Q9NSV4)
Protein diaphanous homolog 3 (Diaphanous-related formin-3) (DRF3) (MDia2)
Gene: DIAPH3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Drf_FH3~Ras, Drf_GBD~Ras
Common GO terms	GO:0005829 - cytosol GO:0043131 - erythrocyte enucleation
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Hs			1 1193
+	Hs
		988751 RAC1_HUMAN (1-192): 3.43e-86: 253: 92.19		DIAP3_HUMAN (1-1193): 0: 1085: 100.00
+	Hs
		601464 RHOQ_HUMAN (4-190): 1.9e-82: 244: 62.03		DIAP3_HUMAN (1-1193): 0: 1085: 100.00
+	Hs
		988853 RAC1_HUMAN (1-192): 3.43e-86: 253: 92.19		DAAM1_HUMAN (87-1104): 0: 757: 26.00
+	Hs
		581391 RAC2_HUMAN (1-192): 1.14e-83: 247: 100.00		DAAM1_HUMAN (87-1104): 0: 757: 26.00
+	Hs
		601514 RHOQ_HUMAN (4-190): 1.9e-82: 244: 62.03		DAAM1_HUMAN (87-1104): 0: 757: 26.00
+	Hs
		581155 RAC2_HUMAN (1-192): 1.14e-83: 247: 100.00		FMNL3_HUMAN (92-1091): 0: 665: 20.44
+	Hs
		988622 RAC1_HUMAN (1-192): 3.43e-86: 253: 92.19		FMNL2_HUMAN (112-1089): 0: 653: 21.45
+	Dd
		757431 RAC1A_DICDI (1-192): 8.71e-83: 245: 78.35		FORH_DICDI (91-1079): 0: 586: 21.75
+	Dm
		828034 RAC1_DROME (1-192): 1.49e-83: 246: 89.06		FRL_DROME (227-1071): 0: 581: 18.84
+	Hs
		252441 RAC1_HUMAN (1-192): 3.43e-86: 253: 92.19		DIAP1_HUMAN (20-635): 3.92e-134: 442: 37.97
+	Hs
		258558 RAC1_HUMAN (1-192): 3.43e-86: 253: 92.19		DIAP2_HUMAN (48-556): 9.07e-132: 432: 58.29
+	Hs
		258546 RAC2_HUMAN (1-192): 1.14e-83: 247: 100.00		DIAP2_HUMAN (48-556): 9.07e-132: 432: 58.29
+	Hs
		258548 RHOQ_HUMAN (4-190): 1.9e-82: 244: 62.03		DIAP2_HUMAN (48-556): 9.07e-132: 432: 58.29
+	Hs
		988403 RAC1_HUMAN (1-192): 3.43e-86: 253: 92.19		INF2_HUMAN (612-1179): 3.53e-123: 412: 22.30
+	Hs
		581080 RAC2_HUMAN (1-192): 1.14e-83: 247: 100.00		INF2_HUMAN (612-1179): 3.53e-123: 412: 22.30
+	Hs
		988862 RAC1_HUMAN (1-192): 3.43e-86: 253: 92.19		FHOD1_HUMAN (130-1175): 1.1e-113: 384: 15.79
+	Dm
		117993 RAC1_DROME (1-192): 1.49e-83: 246: 89.06		M9MRS9_DROME (444-1128): 9.29e-111: 379: 17.80
+	Hs
		988766 RAC1_HUMAN (1-192): 3.43e-86: 253: 92.19		FMN2_HUMAN (595-1059): 8.76e-101: 354: 24.08
+	Hs
		337577 RAC1_HUMAN (1-192): 3.43e-86: 253: 92.19		FMNL1_HUMAN (116-548): 1.05e-80: 289: 17.78
+	Hs
		337556 RAC2_HUMAN (1-192): 1.14e-83: 247: 100.00		FMNL1_HUMAN (116-548): 1.05e-80: 289: 17.78