HitPredict - High confidence protein-protein interactions

Interactor 1: MCP (P15529)
Membrane cofactor protein (TLX) (Trophoblast leukocyte common antigen) (CD antigen CD46)
Gene: CD46

Interactor 2: MCP (P15529)
Membrane cofactor protein (TLX) (Trophoblast leukocyte common antigen) (CD antigen CD46)
Gene: CD46

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Interacting Pfam domains	Sushi~Sushi
Common GO terms	GO:0001618 - virus receptor activity GO:0002079 - inner acrosomal membrane GO:0002250 - adaptive immune response GO:0002456 - T cell mediated immunity GO:0005615 - extracellular space and 19 others more... GO:0005886 - plasma membrane GO:0005925 - focal adhesion GO:0006958 - complement activation, classical pathway GO:0007338 - single fertilization GO:0008593 - regulation of Notch signaling pathway GO:0009986 - cell surface GO:0010628 - positive regulation of gene expression GO:0010629 - negative regulation of gene expression GO:0032733 - positive regulation of interleukin-10 production GO:0035581 - sequestering of extracellular ligand from receptor GO:0038023 - signaling receptor activity GO:0042102 - positive regulation of T cell proliferation GO:0043382 - positive regulation of memory T cell differentiation GO:0045087 - innate immune response GO:0045296 - cadherin binding GO:0045591 - positive regulation of regulatory T cell differentiation GO:0045959 - negative regulation of complement activation, classical pathway GO:0070062 - extracellular exosome GO:0071636 - positive regulation of transforming growth factor beta production
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1	392
Hs

1	392

Service provided by Combinatics, Japan

Last updated: 11Aug2025