Protein: DAF
Complement decay-accelerating factor (CD antigen CD55)

Gene: DAF, CD55
Organism: Homo sapiens
Interactions: 66
UniProt ID: P08174

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0001618 - virus receptor activity
GO:0002726 - positive regulation of T cell cytokine production
GO:0005576 - extracellular region
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

444673

CO2
Complement C2

2

14

High-throughput

0.789

High

437621

HEPS
Serine protease hepsin

1

6

High-throughput

0.691

High

467009

NOTC2
Neurogenic locus notch homolog protein 2

1

5

High-throughput

0.691

High

467043

ST14
Suppressor of tumorigenicity 14 protein

1

11

High-throughput

0.691

High

467005

AGRE5
Adhesion G protein-coupled receptor E5

1

1

Small-scale

0.647

High

467040

AGRE2
Adhesion G protein-coupled receptor E2

1

1

Small-scale

0.647

High

467001

CH3L1
Chitinase-3-like protein 1

3

0

High-throughput

0.629

High

466993

DAF
Complement decay-accelerating factor

1

9

Small-scale

0.575

High

395344

ESR1
Estrogen receptor

2

3

High-throughput

0.571

High

342492

LY86
Lymphocyte antigen 86

1

0

High-throughput

0.513

High

466994

CCL3
C-C motif chemokine 3

1

0

High-throughput

0.513

High

466998

PGFRA
Platelet-derived growth factor receptor alpha

1

0

High-throughput

0.513

High

467016

PDCD2
Programmed cell death protein 2

1

0

High-throughput

0.513

High

467018

HFE
Hereditary hemochromatosis protein

1

0

High-throughput

0.513

High

467031

C1QT7
Complement C1q tumor necrosis factor-related protein 7

1

6

High-throughput

0.489

High

217731

TGON2
Trans-Golgi network integral membrane protein 2

1

5

High-throughput

0.479

High

362622

EGFR
Epidermal growth factor receptor

1

7

High-throughput

0.479

High

410534

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

6

High-throughput

0.479

High

467000

BASI
Basigin

1

2

High-throughput

0.479

High

467011

TRI25
E3 ubiquitin/ISG15 ligase TRIM25

1

1

High-throughput

0.479

High

178149

NPC1
NPC intracellular cholesterol transporter 1

1

0

High-throughput

0.458

High

240528

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

467023

CF120
UPF0669 protein C6orf120

1

0

High-throughput

0.458

High

467033

CHM4B
Charged multivesicular body protein 4b

1

0

High-throughput

0.458

High

466996

CFTR
Cystic fibrosis transmembrane conductance regulator

1

1

High-throughput

0.445

High

467015

NF2L2
Nuclear factor erythroid 2-related factor 2

1

2

High-throughput

0.445

High

467021

PKHA7
Pleckstrin homology domain-containing family A member 7

1

1

High-throughput

0.445

High

467028

MOT10
Monocarboxylate transporter 10

1

2

High-throughput

0.445

High

330585

KI20A
Kinesin-like protein KIF20A

1

7

High-throughput

0.437

High

370961

MYC
Myc proto-oncogene protein

1

2

High-throughput

0.437

High

467008

KIF23
Kinesin-like protein KIF23

1

4

High-throughput

0.437

High

467010

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

1

1

Small-scale

0.437

High

467013

TNIP1
TNFAIP3-interacting protein 1

1

3

High-throughput

0.437

High

467014

KIF14
Kinesin-like protein KIF14

1

2

High-throughput

0.437

High

467029

ESR2
Estrogen receptor beta

1

3

High-throughput

0.437

High

467030

HDAC2
Histone deacetylase 2

1

1

High-throughput

0.437

High

467032

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

2

High-throughput

0.437

High

467034

ECT2
Protein ECT2

1

1

High-throughput

0.437

High

467039

HDAC6
Protein deacetylase HDAC6

1

3

High-throughput

0.437

High

337062

NPT2B
Sodium-dependent phosphate transport protein 2B

1

0

High-throughput

0.426

High

466995

GTR1
Solute carrier family 2, facilitated glucose transporter member 1

1

0

High-throughput

0.426

High

467002

S26A3
Chloride anion exchanger

1

0

High-throughput

0.426

High

467003

S19A1
Reduced folate transporter

1

0

High-throughput

0.426

High

467004

EAA3
Excitatory amino acid transporter 3

1

0

High-throughput

0.426

High

467017

SC5AC
Sodium-coupled monocarboxylate transporter 2

1

0

High-throughput

0.426

High

467035

SO1B3
Solute carrier organic anion transporter family member 1B3

1

0

High-throughput

0.426

High

467038

RHCG
Ammonium transporter Rh type C

1

0

High-throughput

0.426

High

467041

S6A14
Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+)

1

0

High-throughput

0.426

High

467042

FLVC2
Choline/ethanolamine transporter FLVCR2

1

0

High-throughput

0.426

High

467012

NAA25
N-alpha-acetyltransferase 25, NatB auxiliary subunit

1

1

High-throughput

0.407

High

467020

C2D1B
Coiled-coil and C2 domain-containing protein 1B

1

1

High-throughput

0.407

High

467022

PLGT3
Protein O-glucosyltransferase 3

1

2

High-throughput

0.407

High

467027

S43A3
Equilibrative nucleobase transporter 1

1

1

High-throughput

0.407

High

466999

RS4Y1
Small ribosomal subunit protein eS4, Y isoform 1

1

0

High-throughput

0.269

Low

156857

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.249

Low

467019

MIDN
Midnolin

1

0

High-throughput

0.249

Low

467024

UBP48
Ubiquitin carboxyl-terminal hydrolase 48

1

0

Small-scale

0.249

Low

467026

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.249

Low

467036

ANLN
Anillin

1

0

High-throughput

0.249

Low

467037

RNF12
E3 ubiquitin-protein ligase RLIM

1

0

High-throughput

0.249

Low

466997

CCNB1
G2/mitotic-specific cyclin-B1

1

0

High-throughput

0.232

Low

467006

KIF11
Kinesin-like protein KIF11

1

0

High-throughput

0.232

Low

467007

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.232

Low

467025

MFD4A
Major facilitator superfamily domain-containing protein 4A

1

0

High-throughput

0.232

Low

467044

PUS1
Pseudouridylate synthase 1 homolog

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025