HitPredict

Interactor 1: GROU (P16371)
Protein groucho (Enhancer of split m9/10 protein) (E(spl)m9/10)
Gene: gro

Interactor 2: SLP1 (P32030)
Fork head domain transcription factor slp1 (Sloppy paired locus protein 1)
Gene: SLP1

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.600

Property	Details
Experiments	11311161, 14605208
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0030154 - cell differentiation
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 730 Dm			1 322
+	Dm
		594702 GROU_DROME (1-730): 7.6e-174: 517: 100.00		Q961V5_DROME (1-322): 8.21e-132: 379: 99.38
+	Hs
		937620 TLE1_HUMAN (1-730): 2.45e-154: 468: 59.95		FOXG1_HUMAN (119-285): 3.75e-56: 191: 51.50
+	Hs
		1047886 TLE1_HUMAN (1-730): 2.45e-154: 468: 59.95		FOXA2_HUMAN (64-307): 1.02e-55: 189: 28.28
+	Hs
		1048155 TLE4_HUMAN (1-730): 1.65e-154: 469: 60.36		FOXL1_HUMAN (118-282): 1.59e-55: 185: 41.18
+	Hs
		1047808 TLE1_HUMAN (1-730): 2.45e-154: 468: 59.95		FOXL1_HUMAN (118-282): 1.59e-55: 185: 41.18
+	Hs
		1048176 TLE4_HUMAN (1-730): 1.65e-154: 469: 60.36		FOXB1_HUMAN (118-304): 1.13e-53: 180: 32.46
+	Hs
		1047857 TLE1_HUMAN (1-730): 2.45e-154: 468: 59.95		FOXB1_HUMAN (118-304): 1.13e-53: 180: 32.46
+	Rn
		92868 D3ZCM7_RAT (1-730): 4.08e-150: 457: 59.13		FOXG1_RAT (119-285): 3.07e-55: 188: 51.50
+	Mm
		1222115 TLE1_MOUSE (1-730): 4.49e-149: 455: 59.44		FOXG1_MOUSE (119-285): 3.03e-55: 188: 51.50
+	Hs
		1048154 TLE4_HUMAN (1-730): 1.65e-154: 469: 60.36		FOXI1_HUMAN (120-266): 3.79e-50: 172: 40.91
+	Hs
		1047807 TLE1_HUMAN (1-730): 2.45e-154: 468: 59.95		FOXI1_HUMAN (120-266): 3.79e-50: 172: 40.91
+	Hs
		937721 TLE1_HUMAN (1-730): 2.45e-154: 468: 59.95		FOXA1_HUMAN (110-251): 2.81e-49: 172: 39.74
+	Hs
		1047963 TLE3_HUMAN (1-730): 1.79e-144: 443: 56.89		FOXL1_HUMAN (118-282): 1.59e-55: 185: 41.18
+	Hs
		1047961 TLE3_HUMAN (1-730): 1.79e-144: 443: 56.89		FOXC1_HUMAN (99-293): 1.73e-52: 182: 32.66
+	Hs
		1048116 TLE3_HUMAN (1-730): 1.79e-144: 443: 56.89		FOXJ2_HUMAN (99-266): 5.35e-52: 181: 36.69
+	Hs
		1048077 TLE3_HUMAN (1-730): 1.79e-144: 443: 56.89		FOXB1_HUMAN (118-304): 1.13e-53: 180: 32.46
+	Hs
		1047962 TLE3_HUMAN (1-730): 1.79e-144: 443: 56.89		FOXI1_HUMAN (120-266): 3.79e-50: 172: 40.91
+	Hs
		937722 TLE3_HUMAN (1-730): 1.79e-144: 443: 56.89		FOXA1_HUMAN (110-251): 2.81e-49: 172: 39.74
+	Hs
		938010 TLE1_HUMAN (1-730): 2.45e-154: 468: 59.95		FOXA3_HUMAN (120-215): 1.2e-24: 103: 55.21
+	Hs
		938012 TLE3_HUMAN (1-730): 1.79e-144: 443: 56.89		FOXA3_HUMAN (120-215): 1.2e-24: 103: 55.21