Protein: SCOT1
Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial (SCOT) (EC 2.8.3.5) (3-oxoacid CoA-transferase 1) (Somatic-type succinyl-CoA:3-oxoacid CoA-transferase) (SCOT-s) (Succinyl-CoA:3-oxoacid CoA transferase)

Gene: SCOT1, OXCT1
Organism: Homo sapiens
Interactions: 46
UniProt ID: P55809

Gene Ontology (top 5):
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0008260 - succinyl-CoA:3-oxo-acid CoA-transferase activity
GO:0042182 - ketone catabolic process
GO:0046950 - cellular ketone body metabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

878789

SCOT2
Succinyl-CoA:3-ketoacid coenzyme A transferase 2, mitochondrial

3

6

High-throughput

0.861

High

496662

TAU
Microtubule-associated protein tau

2

1

High-throughput

0.628

High

878770

SCOT1
Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial

1

6

High-throughput

0.618

High

878780

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

3

0

Small-scale

0.613

High

226991

PRKN
E3 ubiquitin-protein ligase parkin

2

0

High-throughput

0.559

High

835154

NDUV1
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial

1

0

High-throughput

0.513

High

834253

PSN1
Presenilin-1

1

0

High-throughput

0.486

High

499651

CH60
60 kDa heat shock protein, mitochondrial

1

3

High-throughput

0.479

High

878772

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

1

High-throughput

0.479

High

878773

MPPA
Mitochondrial-processing peptidase subunit alpha

1

1

High-throughput

0.479

High

878776

AUHM
Methylglutaconyl-CoA hydratase, mitochondrial

1

2

High-throughput

0.479

High

878779

PDK1
[Pyruvate dehydrogenase

1

2

High-throughput

0.479

High

262770

CISY
Citrate synthase, mitochondrial

1

0

High-throughput

0.458

High

266684

NDUS3
NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial

1

0

High-throughput

0.458

High

726109

BASI
Basigin

1

0

High-throughput

0.458

High

777514

MDHM
Malate dehydrogenase, mitochondrial

1

0

High-throughput

0.458

High

799190

EFTS
Elongation factor Ts, mitochondrial

1

0

High-throughput

0.458

High

878781

MRM1
rRNA methyltransferase 1, mitochondrial

1

0

High-throughput

0.458

High

878785

PTPM1
Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1

1

0

High-throughput

0.458

High

878786

FMC1
Protein FMC1 homolog

1

0

High-throughput

0.458

High

878787

EFGM
Elongation factor G, mitochondrial

1

0

High-throughput

0.458

High

878788

TR61B
tRNA

1

0

High-throughput

0.458

High

878793

ACAD9
Complex I assembly factor ACAD9, mitochondrial

1

0

High-throughput

0.458

High

878795

MRES1
Mitochondrial transcription rescue factor 1

1

0

High-throughput

0.458

High

878796

PAK5
Serine/threonine-protein kinase PAK 5

1

0

High-throughput

0.458

High

668549

PML
Protein PML

1

1

High-throughput

0.437

High

878775

TIF1B
Transcription intermediary factor 1-beta

1

1

High-throughput

0.437

High

787881

EPS15
Epidermal growth factor receptor substrate 15

2

0

High-throughput

0.328

High

878777

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

0

High-throughput

0.279

Low

878783

JAZF1
Juxtaposed with another zinc finger protein 1

1

0

High-throughput

0.279

Low

878790

B2L14
Apoptosis facilitator Bcl-2-like protein 14

1

0

High-throughput

0.279

Low

225277

AGRB3
Adhesion G protein-coupled receptor B3

1

0

High-throughput

0.269

Low

878794

BMP2K
BMP-2-inducible protein kinase

1

0

High-throughput

0.269

Low

174758

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

0

High-throughput

0.261

Low

346343

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.249

Low

384572

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.249

Low

503767

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.249

Low

817840

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.249

Low

878771

RHOG
Rho-related GTP-binding protein RhoG

1

0

High-throughput

0.249

Low

878774

TFCP2
Alpha-globin transcription factor CP2

1

0

High-throughput

0.249

Low

878778

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.249

Low

878782

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

878784

PRS35
Inactive serine protease 35

1

0

High-throughput

0.249

Low

878792

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

878791

ZDHC5
Palmitoyltransferase ZDHHC5

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024