Interactor 1: TNFA (P16599)
Tumor necrosis factor (Cachectin) (TNF-alpha) (Tumor necrosis factor ligand superfamily member 2) (TNF-a) [Cleaved into: Tumor necrosis factor, membrane form (N-terminal fragment) (NTF); Intracellular domain 1 (ICD1); Intracellular domain 2 (ICD2); C-domain 1; C-domain 2; Tumor necrosis factor, soluble form]
Gene: Tnf
Interactor 2: CASPC (Q920D5)
Caspase-12 (CASP-12) (EC 3.4.22.-)
Gene: Casp12
Species: Rattus norvegicus
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.33 | 0.60 | 0.445 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 17623297 |
| Identification Methods | pull down |
| Interaction Type | association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0002020 - protease binding GO:0009410 - response to xenobiotic stimulus GO:0043525 - positive regulation of neuron apoptotic process GO:0045471 - response to ethanol |
| Homologous interactions | 13 |
Homologous interactions
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025