Protein: TNF10
Tumor necrosis factor ligand superfamily member 10 (Apo-2 ligand) (Apo-2L) (TNF-related apoptosis-inducing ligand) (Protein TRAIL) (CD antigen CD253)

Gene: TNF10, TNFSF10
Organism: Homo sapiens
Interactions: 38
UniProt ID: P50591

Gene Ontology (top 5):
GO:0005102 - signaling receptor binding
GO:0005125 - cytokine activity
GO:0005164 - tumor necrosis factor receptor binding
GO:0005576 - extracellular region
GO:0005615 - extracellular space

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

163260

TR10B
Tumor necrosis factor receptor superfamily member 10B

19

20

Small-scale

0.985

High

127650

TR10A
Tumor necrosis factor receptor superfamily member 10A

5

20

Small-scale

0.908

High

897153

TR10D
Tumor necrosis factor receptor superfamily member 10D

3

20

Small-scale

0.845

High

897144

CASP8
Caspase-8

17

13

Small-scale

0.760

High

897139

FADD
FAS-associated death domain protein

16

16

Small-scale

0.759

High

192998

CFLAR
CASP8 and FADD-like apoptosis regulator

6

13

Small-scale

0.714

High

164910

TR10C
Tumor necrosis factor receptor superfamily member 10C

1

20

Small-scale

0.647

High

533900

IRF1
Interferon regulatory factor 1

2

7

Small-scale

0.601

High

897140

RIPK1
Receptor-interacting serine/threonine-protein kinase 1

2

8

Small-scale

0.584

High

897132

TNF10
Tumor necrosis factor ligand superfamily member 10

1

8

Small-scale

0.575

High

897142

CUL3
Cullin-3

2

0

Small-scale

0.559

High

897148

ZDH17
Palmitoyltransferase ZDHHC17

1

4

High-throughput

0.541

High

563438

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.518

High

840019

CASP3
Caspase-3

1

13

Small-scale

0.501

High

897146

NOMO1
BOS complex subunit NOMO1

1

1

High-throughput

0.489

High

897152

RBM42
RNA-binding protein 42

1

2

High-throughput

0.489

High

277604

H2AY
Core histone macro-H2A.1

1

1

Small-scale

0.479

High

639210

TNAP3
Tumor necrosis factor alpha-induced protein 3

1

3

Small-scale

0.479

High

838021

STAT1
Signal transducer and activator of transcription 1-alpha/beta

1

1

Small-scale

0.479

High

897137

TRAF2
TNF receptor-associated factor 2

1

9

Small-scale

0.479

High

897141

IRF5
Interferon regulatory factor 5

1

7

Small-scale

0.479

High

897143

IRF3
Interferon regulatory factor 3

1

7

Small-scale

0.479

High

897134

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

1

0

Small-scale

0.458

High

897145

PEA15
Astrocytic phosphoprotein PEA-15

1

0

Small-scale

0.458

High

897150

CASPA
Caspase-10

1

13

Small-scale

0.445

High

858575

IEX1
Radiation-inducible immediate-early gene IEX-1

1

0

Small-scale

0.438

High

155924

SOCS3
Suppressor of cytokine signaling 3

1

11

Small-scale

0.437

High

571576

IRF2
Interferon regulatory factor 2

1

7

Small-scale

0.437

High

887400

CEBPD
CCAAT/enhancer-binding protein delta

1

4

Small-scale

0.437

High

897133

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

1

2

High-throughput

0.437

High

897149

PELP1
Proline-, glutamic acid- and leucine-rich protein 1

1

4

Small-scale

0.437

High

897138

PAK1
Serine/threonine-protein kinase PAK 1

1

0

Small-scale

0.426

High

567206

PPA5
Tartrate-resistant acid phosphatase type 5

1

0

High-throughput

0.282

High

897147

RBM48
RNA-binding protein 48

1

0

High-throughput

0.282

High

897135

CCZ1B
Vacuolar fusion protein CCZ1 homolog B

1

0

High-throughput

0.279

Low

897151

RMC1
Regulator of MON1-CCZ1 complex

1

0

High-throughput

0.279

Low

897136

RUNX1
Runt-related transcription factor 1

1

0

Small-scale

0.198

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025