HitPredict

Interactor 1: FGFR2 (P21802)
Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) (Keratinocyte growth factor receptor) (CD antigen CD332)
Gene: FGFR2

Interactor 2: BCAR1 (P56945)
Breast cancer anti-estrogen resistance protein 1 (CRK-associated substrate) (Cas scaffolding protein family member 1) (p130cas)
Gene: BCAR1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36736316
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PK_Tyr_Ser-Thr~SH3_1
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 821 Hs			1 870
+	Hs
		507931 FGFR1_HUMAN (1-820): 0: 772: 71.17		BCAR1_HUMAN (1-870): 2.49e-107: 352: 100.00
+	Hs
		601499 FGFR2_HUMAN (1-821): 0: 863: 100.00		DYST_HUMAN (457-866): 1.71e-67: 248: 12.07
+	Hs
		609231 FGFR3_HUMAN (10-821): 0: 731: 65.69		BCAR1_HUMAN (1-870): 2.49e-107: 352: 100.00
+	Hs
		607932 FGFR4_HUMAN (22-810): 0: 684: 55.86		BCAR1_HUMAN (1-870): 2.49e-107: 352: 100.00
+	Hs
		507961 FGFR1_HUMAN (1-820): 0: 772: 71.17		ACK1_HUMAN (9-499): 2.55e-30: 131: 15.35
+	Hs
		302247 FGFR1_HUMAN (1-820): 0: 772: 71.17		SC31A_HUMAN (101-520): 1.46e-24: 112: 12.97
+	Hs
		508140 FGFR1_HUMAN (1-820): 0: 772: 71.17		SH3K1_HUMAN (7-294): 1.08e-16: 86.7: 16.44
+	Hs
		297957 FGFR3_HUMAN (10-821): 0: 731: 65.69		FCSD2_HUMAN (3-156): 3.32e-24: 110: 24.68
+	Hs
		203204 FGFR1_HUMAN (1-820): 0: 772: 71.17		SYNJ1_HUMAN (281-696): 4.9e-10: 65.7: 13.47
+	Hs
		302255 FGFR4_HUMAN (22-810): 0: 684: 55.86		SC31A_HUMAN (101-520): 1.46e-24: 112: 12.97
+	Hs
		665392 EPHA3_HUMAN (18-778): 3.24e-168: 514: 18.30		DYST_HUMAN (457-866): 1.71e-67: 248: 12.07
+	Hs
		665216 EPHA2_HUMAN (18-798): 4.64e-157: 485: 19.21		DYST_HUMAN (457-866): 1.71e-67: 248: 12.07
+	Hs
		974084 NTRK2_HUMAN (123-765): 4.81e-153: 469: 23.43		DYST_HUMAN (457-866): 1.71e-67: 248: 12.07
+	Hs
		674405 UFO_HUMAN (5-818): 3.59e-160: 490: 22.49		ACK1_HUMAN (9-499): 2.55e-30: 131: 15.35
+	Hs
		992578 NTRK3_HUMAN (166-765): 7.85e-160: 488: 25.31		ACK1_HUMAN (9-499): 2.55e-30: 131: 15.35
+	Hs
		302291 NTRK3_HUMAN (166-765): 7.85e-160: 488: 25.31		SC31A_HUMAN (101-520): 1.46e-24: 112: 12.97
+	Hs
		992580 NTRK2_HUMAN (123-765): 4.81e-153: 469: 23.43		ACK1_HUMAN (9-499): 2.55e-30: 131: 15.35
+	Hs
		665643 EPHB2_HUMAN (9-766): 1.95e-166: 511: 17.58		SH3K1_HUMAN (7-294): 1.08e-16: 86.7: 16.44
+	Hs
		302241 RET_HUMAN (228-816): 2.74e-144: 455: 34.26		SC31A_HUMAN (101-520): 1.46e-24: 112: 12.97
+	Hs
		257545 NTRK1_HUMAN (157-765): 4.6e-143: 443: 25.04		ANR17_HUMAN (67-718): 5.11e-09: 62.6: 9.52