HitPredict

Interactor 1: RHOQ (P17081)
Rho-related GTP-binding protein RhoQ (Ras-like protein TC10) (Ras-like protein family member 7A)
Gene: RHOQ

Interactor 2: IQGA3 (Q86VI3)
Ras GTPase-activating-like protein IQGAP3
Gene: IQGAP3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~RasGAP
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 205 Hs			1 1631
+	Hs
		1290487 RHOJ_HUMAN (9-204): 1.18e-108: 311: 79.59		IQGA3_HUMAN (1-1631): 0: 1710: 100.00
+	Hs
		862984 RHOJ_HUMAN (9-204): 1.18e-108: 311: 79.59		IQGA1_HUMAN (6-1631): 0: 1578: 58.99
+	Hs
		601208 RHOQ_HUMAN (1-205): 3.47e-83: 247: 100.00		IQGA1_HUMAN (6-1631): 0: 1578: 58.99
+	Hs
		862792 RAC1_HUMAN (10-195): 2.03e-80: 239: 63.98		IQGA1_HUMAN (6-1631): 0: 1578: 58.99
+	Mm
		988916 RAC1_MOUSE (10-195): 2.03e-80: 239: 63.98		IQGA1_MOUSE (7-1631): 0: 1547: 58.85
+	Hs
		1111489 RHOJ_HUMAN (9-204): 1.18e-108: 311: 79.59		IQGA2_HUMAN (85-1631): 0: 1358: 42.47
+	Hs
		601277 RHOQ_HUMAN (1-205): 3.47e-83: 247: 100.00		IQGA2_HUMAN (85-1631): 0: 1358: 42.47
+	Hs
		988345 RAC1_HUMAN (10-195): 2.03e-80: 239: 63.98		IQGA2_HUMAN (85-1631): 0: 1358: 42.47
+	Hs
		1129070 RHOJ_HUMAN (9-204): 1.18e-108: 311: 79.59		RASA3_HUMAN (841-1504): 8.42e-106: 360: 13.68
+	Hs
		1433569 RHOJ_HUMAN (9-204): 1.18e-108: 311: 79.59		NGAP_HUMAN (1000-1453): 5.24e-81: 294: 17.18
+	Hs
		988369 RAC1_HUMAN (10-195): 2.03e-80: 239: 63.98		RASA3_HUMAN (841-1504): 8.42e-106: 360: 13.68
+	Hs
		601517 RHOQ_HUMAN (1-205): 3.47e-83: 247: 100.00		MYO5A_HUMAN (699-1556): 5.44e-89: 324: 15.02
+	Hs
		1219091 RHOJ_HUMAN (9-204): 1.18e-108: 311: 79.59		DAB2P_HUMAN (1000-1424): 2.58e-68: 255: 15.03
+	Hs
		601488 RHOQ_HUMAN (1-205): 3.47e-83: 247: 100.00		NGAP_HUMAN (1000-1453): 5.24e-81: 294: 17.18
+	Gg
		1221097 Q6LC82_CHICK (10-195): 2.03e-80: 239: 63.98		ARHG6_CHICK (37-448): 4.06e-76: 272: 11.83
+	Hs
		988435 RAC1_HUMAN (10-195): 2.03e-80: 239: 63.98		DAB2P_HUMAN (1000-1424): 2.58e-68: 255: 15.03
+	Hs
		637954 RHOJ_HUMAN (9-204): 1.18e-108: 311: 79.59		NF1_HUMAN (967-1301): 9.78e-45: 181: 21.57
+	Hs
		601172 RHOQ_HUMAN (1-205): 3.47e-83: 247: 100.00		NF1_HUMAN (967-1301): 9.78e-45: 181: 21.57
+	Hs
		637879 RAC1_HUMAN (10-195): 2.03e-80: 239: 63.98		NF1_HUMAN (967-1301): 9.78e-45: 181: 21.57
+	Sc
		618364 CDC42_YEAST (10-185): 5.83e-85: 251: 66.48		IQG1_YEAST (31-263): 2.64e-26: 120: 24.90