HitPredict

Interactor 1: FGFR2 (P21802)
Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) (Keratinocyte growth factor receptor) (CD antigen CD332)
Gene: FGFR2

Interactor 2: EPN4 (Q14677)
Clathrin interactor 1 (Clathrin-interacting protein localized in the trans-Golgi region) (Clint) (Enthoprotin) (Epsin-4) (Epsin-related protein) (EpsinR)
Gene: CLINT1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005794 - Golgi apparatus GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 821 Hs			1 625
+	Hs
		508002 FGFR1_HUMAN (1-820): 0: 772: 71.17		EPN4_HUMAN (1-625): 2.12e-141: 426: 100.00
+	Hs
		607969 FGFR4_HUMAN (22-810): 0: 684: 55.86		EPN4_HUMAN (1-625): 2.12e-141: 426: 100.00
+	Hs
		508299 FGFR1_HUMAN (1-820): 0: 772: 71.17		EPN1_HUMAN (8-529): 2.46e-67: 231: 23.55
+	Hs
		307502 FGFR1_HUMAN (1-820): 0: 772: 71.17		EPN2_HUMAN (8-595): 6.55e-52: 191: 20.40
+	Hs
		872443 EPHA5_HUMAN (18-766): 3.48e-163: 502: 17.53		EPN4_HUMAN (1-625): 2.12e-141: 426: 100.00
+	Hs
		203204 FGFR1_HUMAN (1-820): 0: 772: 71.17		SYNJ1_HUMAN (120-617): 7.92e-35: 143: 10.29
+	Hs
		1057047 NTRK3_HUMAN (166-765): 7.85e-160: 488: 25.31		EPN4_HUMAN (1-625): 2.12e-141: 426: 100.00
+	Hs
		1057046 EPHA7_HUMAN (64-791): 2.59e-157: 486: 19.23		EPN4_HUMAN (1-625): 2.12e-141: 426: 100.00
+	Hs
		434196 RET_HUMAN (228-816): 2.74e-144: 455: 34.26		EPN4_HUMAN (1-625): 2.12e-141: 426: 100.00
+	Hs
		307505 FGFR4_HUMAN (22-810): 0: 684: 55.86		EPN2_HUMAN (8-595): 6.55e-52: 191: 20.40
+	Hs
		384843 NTRK1_HUMAN (157-765): 4.6e-143: 443: 25.04		EPN4_HUMAN (1-625): 2.12e-141: 426: 100.00
+	Hs
		434323 RET_HUMAN (228-816): 2.74e-144: 455: 34.26		EPN1_HUMAN (8-529): 2.46e-67: 231: 23.55
+	Hs
		307509 EPHA2_HUMAN (18-798): 4.64e-157: 485: 19.21		EPN2_HUMAN (8-595): 6.55e-52: 191: 20.40
+	Hs
		385817 NTRK1_HUMAN (157-765): 4.6e-143: 443: 25.04		EPN1_HUMAN (8-529): 2.46e-67: 231: 23.55
+	Hs
		384551 NTRK1_HUMAN (157-765): 4.6e-143: 443: 25.04		SC24C_HUMAN (288-606): 1.21e-10: 66.6: 8.96
+	Bt
		94410 F1MWF1_BOVIN (4-373): 7.22e-19: 94.4: 16.71		F1N579_BOVIN (8-548): 7.3e-68: 233: 22.84
+	Mm
		729410 VGFR3_MOUSE (42-378): 3.4e-17: 88.7: 17.77		EPN2_MOUSE (8-555): 6.06e-69: 236: 18.81
+	Hs
		729401 VGFR3_HUMAN (42-385): 5.85e-18: 91.4: 17.62		EPN1_HUMAN (8-529): 2.46e-67: 231: 23.55
+	Mm
		729409 VGFR3_MOUSE (42-378): 3.4e-17: 88.7: 17.77		EPN1_MOUSE (8-529): 2.71e-64: 223: 24.30
+	Hs
		729709 VGFR2_HUMAN (46-363): 1.44e-11: 70.5: 16.82		EPN1_HUMAN (8-529): 2.46e-67: 231: 23.55