HitPredict

Interactor 1: MED14 (P19263)
Mediator of RNA polymerase II transcription subunit 14 (Glucose repression regulatory protein 1) (Mediator complex subunit 14)
Gene: RGR1

Interactor 2: MED7 (Q08278)
Mediator of RNA polymerase II transcription subunit 7 (Mediator complex subunit 7)
Gene: MED7

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.969

The method score is based on:

Property Details
Experiments 11805826, 9891034, 11555651, 10082564, 9710620, 16429126, 37968396, 9420330, 26317468, 28575439
Identification Methods tandem affinity purification, affinity chromatography technology, biochemical
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Med14~Med7
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003712 - transcription coregulator activity
GO:0005634 - nucleus
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0016592 - mediator complex
and 5 others

more...
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 1082
Sc

1 222
+ Dm
+ Hs
+ Ca

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024