Interactor 1: COF1 (P23528)
Cofilin-1 (18 kDa phosphoprotein) (p18) (Cofilin, non-muscle isoform)
Gene: CFL1

Interactor 2: DEST (P60981)
Destrin (Actin-depolymerizing factor) (ADF)
Gene: DSTN

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Cofilin_ADF~Cofilin_ADF
Common GO terms GO:0005737 - cytoplasm
GO:0015629 - actin cytoskeleton
GO:0030042 - actin filament depolymerization
GO:0030043 - actin filament fragmentation
GO:0051014 - actin filament severing
and 2 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 166
Hs

1 165
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024